May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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real democracy at work here, which muslim outfit is supporting Pakistan and raising anti Indian slogan, if he has any proof he can register a case, why would he keep talking like this when central is with him… but instead !!he is just bul@#$ing to impress those people, who except every what’s app post as proof...RSS had gifted gun to the first terrorist in independent India and like-minded have also made a temple recently for nathuram goadse- rss was also banned for several years, they were against national flag also...and such organisation is still available then why not SDPI????,,tumhara talwar legal hai aur hamara ,chaku illegal ??
as per Hindutva workers they are not working for India they are working for their political masters, so if they commit crime should they be acquitted. Do you know who is making this arrests they are Hindus they are people like us, who put the country first and will arrest any amar akabar Anthony regardless of political masters or religion…
This foul mouthe KSE should know who hoisted Pak flag in Sindagi, where was this Eshwar when Sri Ravi Shankar shouted Pakistan Zindaba infront of Rajnath Singh, defence minister who remained deaf and dumb. Who went to Pakistant without invitation to eat Beef Biryani in wedding and who took Sari and Bangles as gift to Pakistanis. BJP's IT cell in MP caught passing sensitive defence information to ISI which resuted in death of hundreds of our brave soldiers. You anti-national Sanghi scums are a disgrace to human race. Dont open your ugly mouth, you dirty creature now talk about private part of Muslim males, shame on you brain dead .....
Marle... Looks like escaped from mental hospital.
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