Mangalurean Amoghavarsha Bhat enters ‘Voice of UAE 2017’ finale

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

New Delhi, Jun 8: Two civil defence employees have been arrested by the Rajasthan Police today in Jaipur based on Military Intelligence (MI) inputs that they had been passing on sensitive information to Pakistan's spy agency ISI.

The arrested are: Vikas Kumar (29), a civil defence employee at an army ammunition depot near Shri Ganganagar (Rajasthan) and Chiman Lal (22), a civil contractual employee of the army's Mahajan Field Firing Range (MFFR), Bikaner. 

Both were working as espionage agents on behalf of Pakistan's intelligence agency and were giving out details of Ammunition and MFFR, vital military installations in India's Western front. 

The MI Lucknow's operation named Desert Chase assumes great importance as the Shri Ganganagar Ammunition Depot and Bikaner MMFR are strategically important military installations on the western front along the Pakistan border.

The work on the "operation" began in August 2019, when the MI Lucknow, through its sleuths, learnt about an espionage agent near Sri Ganganagar who was passing military information to his handlers in Pakistan. The individual was identified as Vikas Kumar - the civil defence employee at an army ammunition depot near Sri Ganganagar.

The MI Lucknow shared the case with UP ATS in the month of January 2020. Vikas's activities were monitored and analysed by a joint team of MI Lucknow and UP ATS. The operation was code-named 'Desert Chase'.

Based on these, it was learnt that Vikas is acquiring photos of a "water distribution register" at a water point/pump house in MFFR through a contractual civil employee named Chiman Lal. The development of the case was halted due to the start of the lockdown period all across the country.

Finally, the case shared with Rajasthan Police Intelligence in the first week of May 2020. A joint team was formed between Rajasthan Police-Intelligence and MI Lucknow.

Fresh leads were found as new payments were detected along with a trail of sensitive information being passed on to Pakistan by two accused.  

Vikas Kumar confessed to having passed the following information to Pakistan:

•    Details received from Chiman Lal about Army units and their strength coming to MFFR.
•    Details of ammunition coming to his ammunition depot including their type, quantity, mode of transportation, date of arrival on a routine basis (almost every time it came to his notice).
•    Details of ammunition (to include their type, quantity and mode/date of transportation) further distributed/transferred to local army establishments/units (including two local brigades) and elsewhere from his ammunition depot.
•    ORBAT (Order of battle; composition related details) of two local army brigades and all changes in them as they came to his notice.
•    Name, rank and personality traits of some Senior Military Officers in the two army brigades nearby, his ammunition depot and others who visited the military station.
•    Photos of arms, ammunition, tanks other military vehicles (with their tactical numbers) at MFFR whenever he could visit it after April 2019.

Vikas also confessed to having received at least Rs 75,000 in total from his Pakistani handler for the information he has shared during this entire period. He used to receive them mostly on bank accounts of his and his brother, Hemant Kumar. The latter was found to have no links to the espionage case otherwise. Out of this sum, he had paid approximately Rs 9,000 in total to Chiman Lal for his assistance in lots of Rs 1000- Rs 2000 since their first meet.

Tumkur, Jan 10: A five-year-old boy has been killed by a leopard in Gubi taluk of Tumkuru district in Karnataka.

The local police said today that the incident took place on Thursday evening when the boy was returning home along with his grandmother.

The leopard first attacked a cow and then the boy who was behind it. The feline dragged the body into the forest.

After a search operation by the forest officials, the body was found and handed over to the parents after post-mortem.