How a hatemonger used a schoolgirl to concoct a stabbing story to create unrest in Honnavar

Beijing/Zurich, Mar 4: China has approved the use of Swiss drugmaker Roche's anti-inflammation drug Actemra for patients who develop severe complications from the coronavirus as it urgently hunts for new ways to combat the deadly infection that is spreading worldwide.

China is hoping that some older drugs could stop severe cytokine release syndrome (CRS), or cytokine storms, an overreaction of the immune system which is considered a major factor behind catastrophic organ failure and death in some coronavirus patients.

Actemra, a biologic drug approved in 2010 in the United States for rheumatoid arthritis (RA), inhibits high Interleukin 6 (IL-6) protein levels that drive some inflammatory diseases.

China's National Health Commission said in treatment guidelines published online on Wednesday that Actemra can now be used to treat coronavirus patients with serious lung damage and high IL-6 levels.

Separately, researchers in the country are testing Actemra, known generically as tocilizumab, in a clinical trial expected to include 188 coronavirus patients and running until May 10.

Roche, which donated 14 million yuan ($2.02 million) worth of Actemra during February, said the trial was initiated independently by a third party with the aim of exploring the efficacy and safety of the drug in coronavirus patients with CRS.

It added that there was currently no published clinical trial data on the drug's safety or efficacy against the virus.

More than 3,000 people have died and 93,000 have been infected by the novel coronavirus thought to have originated in Wuhan, China, before spreading to around 90 countries including the United States, Italy, Switzerland, France and Germany.

The Swiss company, for which China is its No. 2 market behind the United States, also makes diagnostic gear to detect the coronavirus.

Since Actemra's approval a decade ago, it has become a go-to drug against other inflammatory conditions, including cytokine storms in cancer patients receiving cell therapies from Novartis and Gilead Sciences.

In 2012 it helped save the life of a young U.S. girl, the first child to be treated for leukaemia with Novatis' Kymriah, from a post-treatment rush of IL-6.

Priced at between $20-30,000 annually for RA according to SSR Health, Roche's medicine is also used for rare juvenile arthritis and giant cell arteritis, or inflammation of the blood vessels.

Mangaluru, Apr 22: Dakshina Karnataka District in-charge Minister Kota Srinivas Poojary on Wednesday warned of invoking Goonda Act against those who attack doctors, police or ASHA workers who are involved in the fight against the Covid-19 pandemic.

Addressing a function arranged to distribute food kits to journalists on behalf of SCDCC Bank at the Patrika Bhavan on Wednesday, the Minister said the authorities have been instructed to initiate action without any hesitation against anyone who tries to attack Corona warriors.

It has been observed across the state the incidents of attack and assault on ASHA workers, police and civic workers are increasing hence it was felt the need for severe actions against such elements , he added.

Belagavi, Apr 19: Veteran writer and Translator Chandrakanth Kusnoor passed away in his house on Sunday due to age-related disease.

He was 90.

He was survived by wife, four sons and one daughter.

According to family sources, the last rites were held in the wee hours of Sunday.

Mr Kushnoor, a multi-faceted personality, maybe the one of the few who had won the Karnataka Nataka Academy, Karnataka Lalitha Kala Academy and Karnataka Sahitya Academy awards for his works as writer, translator, novelist, poet, playwright, painter, art critic and institution builder.

He had translated many books from Kannada (late U R Ananthmurthy and Srikrishna Alanahalli) into Hindi, and other books into Marathi and Urdu.

He was among the pioneering abstract writers in Kannada. His plays like Dindi, Vidushaka, Ratto Ratto Rayara Magale and Ani Bantu Ondu Ani, were widely performed.

His biographical novel Gohar Jan chronicles the growth of professional theatre music tradition.

He had converted his home in Channamma Nagar into a mini art gallery and used to paint till recently. He hailed from Kalaburagi where he worked as a college professor for some years. He had settled in Belagavi after his retirement as the Deputy Director of Kannada and culture.

He had won the Karnataka Rajyotsava Award.