May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Totally comdemenable situatation, at Kottara chawki Criminal Killer from {Kadapu} kerala Uppala and Kunjuttur, all very young boys ,here in natakel Sangi Criminal Jihadi came from Sullia, you people understand all these safroon criminal leaders understand their utterely defetables forth comming election, Yeddianna and shobakka behind all these, no worries we will produce more and mor, Criminilising the holy land of Hindustan they have t have to pay for ever.
Jai Hoo Siddanna
Jai hoo Raianna.
Dear Bro...
Being a Muslim, lets not drag the Issue much. Yes we all agree it is a criminal act of couple of men who want to disturb the peace in society. We as muslims, try our best to teach them islamic way of handling it. Do u know the Hadees of where a Yahudi is given shelter in the mosque by Rasool ( S.A. ) and the next day morning, he urinated in Masjid and went. But our Rasool S.A. asked sahaba to clean the floor by pouring water on them and asked not to harm the yahudi who urinated there. Lets be the followers of this Great Rasool and lets not make fitna in the society just becoz few are doing some crime.
The place called SULIA is the second HQ of criminal RSS. Dept must trap thier all telecom round the clock and smash this evil from the base. Due to last weeks criminal goonda giri TWO innocents lost their life and whole Mangloreans still with that pain. Beside these desh drohi still stick with their anti communal activity. Now they will create more and more by sponsored goonda giri. SInce the State Govt and our Police Dept are with thier strict action these criminals never succeed much. Public must catch and puch from top to bottom first and hand over to police.
The main culprits behind this are our elected TWO criminal back ground politicians.
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