May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Yedi & Shoba Always to be in Media with no Reason. Why is Media promoting when BJP says Madrasa is giving rise to Terrorist. Media is blowing things out of propotion. What happend with Hemanth Karkere(HK)? Who Killed him? He was telling the news of actual terrorist in India. Hope everyone remembers what HK revealed. I dont support any of the party. But BJP did biggest blunder by doing demonitization. Just to make their money white. People please grow up. See the Petrol price HIKE happening. Why SHELL petrol does not have Subisidy? Why GST is not introduced in Petrol ? There are so many things to think about. These people play with law & order. See yeddy is so confident giving Dhamki to Police. Only god can Save us !!!
The common man of India is struggling for fulfilling his basic needs, he wants peace, he does not need leaders who divide society on caste and religious grounds and create chaos and hatred in the country.
Well said, Most of the BJP leaders are responsible to created violation.
Statistics show that more Indians have been killed by RSS than by Pakistani terrorists.
Who then is worse?
Is she a member of parliment or she a member of RSS, I havent seen any statement from shobha who has talked of development from her mouth. every time her statement is about RSS/sangh parivar, Does she deserve a MP seat? its better she owes her full time to RSS intead of being a MP. Shame on her she represents the whole constituency not only RSS AND SANGH PARIVAR TERRORISTS
what STRATERGY to DISTURB PEACE OF OUR NAMMA NADU KARNATAKA
Fact is a fact, why Amit shah is not in the group,who is the main culprit holding 14 muderes on his head
"BJP gay nachgayne Illa",
if they have little shame left all these leadres would have not come to street with head's down for their super leaders who committed the crimes,
Indirectly it shows that they confirms what Mr Siddaramaih says..!!!
"nanu BJP nanu RSS", not full
"nanu BJP nanu RSS nanu BrahminBaniaJumlaParty", better!!!
Hindus beware of Brahmin Domination in RSS, they dominated exploited non-brahmins for past 5000 years, dont let them control us!!!
All are equal in Democracy, RSS is a Rascist organisation, majority leaders are Brahmins! Dont forget!!!
Congis are ######s, they were responsible for 1984.
Bjp are ######s, they were responsible for 1992, 2002.
Indira made a political decision, bad decision BUt a political one.
Advani, Joshi, Uma bharati gave speeches in Ayodhya which started riots killing of 3000 people.
Both parties have blood on their hands.
Both need to be sacked and someone better needs to be brought in.
@Truth
Excellent question. The current vicious atmosphere is because of them
Who perpetrated 1984 anti-sikh riots? RSS?
Good decision. Please go and sit in jail.
Nanu shoba matthu yediyurappa naau bjp rss bajarang te ... r.. r ... t ect.....
Another comedy by Sho-bokka. Please try a good mimicry
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