May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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I do not know why media is making some big issues. Most of us have many FB accounts, Email Ids. This is not like Aadhar or Passport where it is the identity. Even in US, I know many senators having many FB accounts. They cannot share their personal details on FB so they have personal, political and regular friends.
Its not your fault. Politics isn't your cup of tea. It is something that is beyond your abilities! Sumne acting madkond iddidre yeshto chennagittu alva? Why on earth do you need all this? Is it worth?
...she just wanted to follow Kejribhai and thought abusing Modi would be a good idea...poor thing paid for it....the way it looks spandana will now onwards beat slower and more sensibly...
When will Ramya make public her smart strategy to take over Nehru dynasty to become all-powerful in Congress party and announce her secret master-stroke engagement to Rahu ?
I like her witty tweet and proud of her success she achieved at young age. She is more smart courage than feku supporter stone aged most superstious backward mindset RSS criminals (especially pucking uneducated ignorant brainwashed male and from mangalore chaddi taliban region) from karnataka. Best part, she doesn't give rats to 1000s of hate, abuse message from 3rd class chaddi criminals. RSS
criminal hurt by fact! RAT that how smart Ramya treat trolls on her facebook and twitter. you low life coward chaddi criminals can intimate her with her and demolishing comments? get a life
manipulating videos is the history of Brahmin Bania Jumla Party! They did it in JNU, they did with Hardik Patel, they might have done now, they will continue doing always
ತಾಯಿ ರಮ್ಯಾ ದೇವಿ ! ಎಷ್ಟು ಶತದಡ್ಡಿ ಇದ್ದೀಯಮ್ಮಾ ನೀನು !? ಅಯ್ಯೋ ಪೆದ್ದಿ, ಮುಂದೆ election ಗೆಲ್ಬೇಕು ಅಂತ ಇದೇಯೋ ಅಥವಾ ಪಪ್ಪು ಆಗ್ಲೇ ರಾಜ್ಯಸಭೆ seat ready ಇಟ್ಟಿದಾನೋ?
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