Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
one of the chut#yst man i ever seen in this news portal..do you think modi is internet email so all the people with him...first change your cow dunge to human brain and come to mangalore for treatment...
Doctor name Dr Kamath surgen 9967453786...
is it ok for you to replace with bakra brain...then dont blame muslim for that..reason we have sortage of human brain due to election
Ananth Kumar, what have you done for the people other then living the life style of the rich and famous with the poor tax payers money and warming up your seat. Nobody can match Siddaramiah he has done 100 foldes of you guys had done.. BJP leaders have nothing tangable to show that's why you guys keep bring up the watch issue. Please vote for Congress! so Siddaramiah can be our CM for a better future for the people of Karnataka.
Moustache still black by the grace of Kolesston colour but Laak chupawo Chupna sakegha Jhoota bjp walon ka jhoot ka chehra. Shakuni mamoo next mp election u will not be anywhere in Karnataka Map.
Wait and watch. first leg will be within a week and the final leg 2019 supda saap no adress of bjp or rss or u.
Anant, thu kasan sangtha maraya, lutha bais. 15 May pale Kazan zatha mum. Yeddi che chaddi votha.
Dear Ananthkumar, you are able and fit leader to be next CM of karnataka. You are always tellig the truth and open to all. We, the people of your constituency fully support you as our care taker and helping us. You are like our God Father.
Anant Kumar is 100 percent correct. Cogress will not get a single seat against the wave's of MODI and YOGI. Our great national hero leader PM Modi has already told that people of Karnataka have made their mind to kick out Congress and select only BJP in karnataka and to be followed by Kerala, Tamil Nadu and Andhra. I think Electon Commission should stop voting in Karnataka to save billions of Rupees as people have already informed our Leader great Modi that they will vote for BJP only. It will be a waste of money for Congress and other parties also as BJP is going to sweep almost all the seats. Our PM is a great astrologer and has dreamt about the win in Karnataka and whatever he dreams it comes true. He had dream of becomingPM of india and it became true. He also dreamed that he will visit also all the countries in the world and its nearly completing as he has left only few countries to visit. Jai Modi ji . Jai Hind.
All Bjp leadrs are day dreaming for power in karnataka which will end on 15th may 2018.Let them happy upto that day. JAI KARNATAKA JAI INDIA.NO FEAR INDIA IS OUR SLOGAN.
Ananth Kumar and Anant Kumar Hegde, both are same in mindset. always spits nonsenses
A study shows BJP is 'richest' political party and the money not in the name of party it's owned by BJP leaders individually. They are not showing it while filing nomination and they are not paying income tax also
The irony is, cow dung fools are criticising normal people
Soon BJP will be eradicated from India due to Computer baba, rapist BJP MLAs, Yogi and Feku etc
In other countries, ministers and elected persons will be highly qualified specific area focused people. Here in India, all BJP MLAs and ministers are some cow dungs
India will be free of BJP due to Modi and his MLA fools
I am not a supporter of any political leader or party. But yeah i'll definitely choose a candidate wisely while voting irrespect of his caste or party.
Mr. Ananth kumar what you know about the facilities the present govt has provided for the farmers by sitiing in Delhi?
Mr. Siddu ( I am not a suppoter of him anyway) has done Something for the farmers of his state. Dont blindnly fool the people of karnataka.
Its sad that farmers are ending their lives all over India..
Add new comment