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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Apr 25: Former Karnataka Health minister and senior Congress leader Dr H C Mahadevappa on Saturday urged the state government to chalk out a comprehensive plan to conduct tests among the vulnerable sections in the society to impede the spread of the dreaded COVID-19 pandemic in the state.

Speaking to media persons, Dr Mahadevappa, felt that only restricting people to remain indoors will not suffice to tackle the spread of the contagious disease he said that "There needs to step up testing the people especially belonging to the vulnerable sections of the society".

Maintaining that the COVID-19 disease, which has progressed itself as a pandemic, across the globe, former Health Minister said that "there is also a need to fight the menace with multiple dimension, as it has potential to cause damage not only the social life of the people but also their livelihood".

Bengaluru, May 25: Karnataka Chief Minister B S Yediyurappa on Monday greeted the Muslim brethren on the occasion of Eid-ul-Fitr, which is being celebrated in a subdued manner due to coronavirus related restrictions.

"Warm greetings of Eid-ul-Fitr. May this festival of peace and harmony bring happiness in life," Yediyurappa said in his message.

He congratulated the Muslim fraternity for cooperating with the authorities by offering prayers at home during the holy month of Ramadan and supporting the government to contain COVID-19.

"I hope the same trend will continue during the festivities of Eid-ul-Fitr too. I thank you all for your support in the fight against COVID-19," he said.

The Eid festivities were a low-key affair as Muslim brethren celebrated the festival indoors in view of lockdown to contain coronavirus on Monday.

People offered the special prayers inside their houses instead of performing it in mosques and Eidgah, the open field to perform prayers, and refrained from going out to greet each other.

As the Karnataka government has ordered Sunday Curfew throughout the lockdown-4 till May 31, the otherwise bustling markets in the urban areas of Karnataka remained shut.

People could not venture out to make necessary purchases on Sunday.

The Jama Masjid of Bengaluru at the City Market had asked the Muslims to offer prayers inside their houses and not go to the burial grounds to express their sentiments for the departed souls.

"Mass prayers are not allowed anywhere in Karnataka. Just five important persons managing the mosques offered the prayers. Similarly, people go to the graveyard to pray for the dead ones but this time we asked people to express their sentiments from inside their homes instead of going to the burial grounds," Maulana Maqsood Imran, the Khateeb-O-Imam, Jama Masjid, Bengaluru, told news agency.

He said, "coronavirus is spreading very rapidly in our country. If we don't follow the guidelines, it will not only cause trouble to us but also to the doctors and the government. It will be the biggest celebration if we abide by the norms."