COVID-19 Vaccine: UK to begin human trials on April 23; pumps in GBP 20 mn for project

A shrimp seller at the wet market in the Chinese city of Wuhan believed to be the centre of the coronavirus pandemic, may be the first person to have tested positive for the disease, a media report said on Saturday.

The report by the London-based Metro newspaper said that 57-year-old woman, named by the Wall Street Journal as Wei Guixian, was selling shrimp at the Huanan Seafood Market when she developed what she thought was a cold last December.

Chinese digital news outlet, The Paper has said that she may be epatient zero'.

Wei was told by doctors her illness was "ruthless" and other workers at the market had come to the Wuhan Union Hospital with the same symptoms, the Metro newspaper report quoted the outlet as saying.

"Every winter, I suffer from the flu, so I thought it was the flu," the woman was quoted as saying by The Paper news outlet.

The shrimp seller added that she believed she contracted the coronavirus from the shared toilet in the market.

She said the fatal disease would have killed fewer people if the government had acted sooner.

Wuhan Municipal Health Commission has confirmed that Wei was among the first 27 people to test positive for the coronavirus.

It said she was one of 24 cases with direct links to the market, the Metro newspaper reported.

Though Wei may be "patient zero", it does not mean she is the first person to have contracted the virus, added the Metro report.

Chinese researchers have claimed that the first person diagnosed with the airborne virus had no contact with the seafood market and was identified on December 1, 2019.

Wei was later quarantined when a connection was made between the bug and the market before recovering in January.

As of Saturday, the global number of coronavirus cases stood at 104,837 with 27,862 deaths, according to the latest update by the Washington-based Johns Hopkins University.

The US has the highest number of cases at 104,837, followed by Italy 86,498 and China 81,948.

Italy has recorded the highest number of fatalities with 9,134 deaths, followed by Spain and China, at 5,138 and 3,299, respectively.

Italian researchers have claimed that they have successfully developed a vaccine to contain coronavirus (COVID-19) which is likely to work on humans, a report said.

Luigi Aurisicchio, CEO of Takis, the firm developing the medication, said that a coronavirus candidate vaccine has neutralised the virus in human cells for the first time, the Arab News reported.

"This is the most advanced stage of testing of a candidate vaccine created in Italy. Human tests are expected after this summer," Aurisicchio was quoted as saying to Italian news agency ANSA.

"According to the Spallanzani Hospital, as far as we know we are the first in the world so far to have demonstrated neutralisation of the coronavirus by a vaccine. We expect this to happen in humans too," he added.

The researchers experimented with the vaccine on mice that had successfully developed antibodies that blocked the virus from infecting the cells. They further observed that the five vaccine candidates generated a large number of antibodies, and selected two with the best results.

All of the vaccine candidates currently being developed are based on the genetic material of DNA protein "spike", the molecular tip used by the coronavirus to enter human cells.

They are injected with the so-called "electroporation" technique, which consists of an intramuscular injection followed by a brief electrical impulse, helping the vaccine break into the cells and activating the immune system, the report said.

Researchers believe that this makes their vaccine particularly effective for generating functional antibodies against the "spike" protein, in particular in the lung cells, which are the most vulnerable to coronavirus.

"We are working hard for a vaccine coming from Italian research, with an all-Italian and innovative technology, tested in Italy and made available to everyone," Aurisicchio was quoted by the Arab News report.

"In order to reach this goal, we need the support of national and international institutions and partners who may help us speed up the process," he noted.

The total number of COVID-19 infections, fatalities and recoveries since the pandemic began has risen to 213,013 in the country.

Washington, Apr 20: The US wants to send a team of experts to China to investigate coronavirus, President Donald Trump has said, a day after he warned Beijing of "consequences" if it was knowingly responsible for the spread of COVID-19 which has killed more than 165,000 people globally, including over 41,000 in America.

Describing the coronavirus as a plague, Trump, during his White House news conference on Sunday, said that he is not happy with China where the pandemic emerged in December last year in the central Chinese city of Wuhan.

“We spoke to them (Chinese) a long time ago about going in. We want to go in. We want to see what's going on. And we weren't exactly invited, I can tell you that,” the President told reporters.

“I was very happy with the (trade) deal (with China), very happy with everything and then we found out about the plague and since we found out about that I'm not happy,” he said.

The US has launched an investigation into whether the deadly virus "escaped" from the Wuhan Institute of Virology.

He has repeatedly expressed disappointment over China's handling of the coronavirus disease, alleged non-transparency and initial non-cooperation from Beijing with Washington on dealing with the crisis.

“Based on an investigation, we are going to find out,” Trump told reporters.

A day earlier, he warned China that it should face consequences if it was "knowingly responsible" for the spread of the novel coronavirus, upping the ante on Beijing over its handling of the COVID-19 pandemic.

“If they (China) were knowingly responsible… then there should be consequences. You're talking about, you know, potentially lives like nobody's seen since 1917,” Trump said on Saturday.

The opposition Democratic Party said that Trump has falsely claimed he acted early by restricting travel from China when it was little too late and he continued to downplay the virus throughout February.

The number of COVID-19 deaths in the US crossed 41,000 and the total infections were more than 764,000 so far.

New York, the epicentre of the deadly COVID-19 in the US, has 2,42,000 cases and over 17,600 fatalities so far. It has registered a 50-percent decline in new cases over an eight-day period.

The novel virus, which emerged in China in December last year, has killed over 160,000 and infected more than 2.3 million people worldwide.