May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Mr.Bajarangi,Mr.Modi declared 80%of cow vigilantes as hooligans.Hope you know his address so that you can go to his home if you have damm.
It is sad to read some of the above comments. There should not be such low level comments.
Every Hindus are not fake gow rakshakas and every muslims are not cow smugglers.
I request all brothers of DK and Udupi to respect each other and we should live peacefully in our beautiful land.
These cow protectors do not have ba**s.....
@kiran bajarangi nikh popunda maga
Kiran Bajrangi ..... I know that is your DNA... Not a surprise ... Barking dogs do not bite .... There is no need of my address,, Give your address I will come to your home, to make your job easy....
@ kiran bajarangii
u people are good for these type of work only,
naam patha dehta tho thu ayenga kya .. u wil come wen liquer enter ur stomach... dar pok thuu be
We can feel the frustration in Kiran bajarangi's comments. Calm Down Bajarangi. Before you attack Slaughter house please make sure that no one from your group work their as a KASAI.
Kiran Bajrangi,
Gidad ki jab maut aati hai to wo sheher ki taraf baghta hai. Bajrangi Kasai khane ki taraf.
All these self styled gau rakshaks are un employed, uncultured goons
And they always attack one person in a group of 30-50 people... bcos they actually dont have guts to attack in small numbers for fear of their life ...
Congress is in power. Yet they can't take action against cow terrors.??? They are only limited to issuing press release and petitions, then who is controlling the govt.administrations??? CongRSS or BJP..??
Kya hum bewakoof hain..??
Mr.SK pura naam patha bejo darr pok, will come to your home and beat u.
@ Kiran Bajarani Bhaijan,
What a JOKE. We would like to see you in Slaughter House. Sharan Pumpwel please bring your Ambulance not the ARMY to protect your Bajarangis. All the Best. Abb ayega real Maza
abey saaley me dikatha hoon kithna dum he bolke samne ake dekho kuthe.
Kiran Bajrangi......Pls go ahead ....all the BEST.....let us see, who is your real MATHA....
KIran thumare gaand me dum hai tho slaughter house ko attack karkre dikana. Your 10 people attack a single person.
thanks for the information ivan, Next time we will directly attack slaughter houses.
Ivan at his best, agree this is what happening in india,
mainly this bajrangis are eating 90% of beef in india,
all beef business contact should be given to bajrangdal, then they will be happy.
yahh rightly said MLA saab 'Cows ‘rescued’ by vigilantes in coastal Karnataka end up in slaughterhouses'
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