Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
9/11 caused more Americans to embrace Islam.
The same thing happens here, more Truth Loving people start researching the speech of Zakir Naik and will easily embracing Islam.
Indians are more free and intelligent in deciding.
Unfortunately the RSS lead govt can detain him under pretext of so called all allegation, even without proof.
We have some blind law where innocent people become easy prey.
Such law is made to target the people who talks truth against the corrupt leaders.
Laks...Karkala.....
Every one knows you hypocrites are experts in fabricating proofs and give clean chit to criminals ...... Indians can eat indian cow meat in Gulf BUT not in India.... Go to Google and find out the names of Indians in the list of TOP CRIMINALS of the world ....Hypocrite ....
Laks, Karkala
From your frustrated comments i can understand that you are so far from the reality. Not a single proof can indian govt can show against Dr.Zakir naik. Even nobody can have the guts to have debate with zakir naik. so will wait and watch.
Laks, Zakir Naik did not trouble anyone...when he was preaching around everyone lived very happily here in India....He conveyed peace message to everyone...
Dear Altaf,
Dont teach us what to ban...Our present government have enough proof to put him behind the bar...and your lawyer is der to protect him..so leave it to court
Sitting in Doha its easy for you to comment
Basically it is not the matter of scare. In the recent years we have noticed that the Muslims are targeted & put behind bars without any evidence.
Later it is proved that the RSS goons are involved in the terror activity across the country. But they are not booked in any case.
These types of double standard Judicial System makes the Muslims to be away for certain period. I hope very soon Br. Zakir Naik we get justice & start spreading the peace message.
Mr. Zakir Naik's Preaching, Knowledge and popularity not gone well with sick minds, they cannot counter him through dialogue; obviously misuse of power is the solution!!!
Laks, Karkala
If you really wish to see that everyone in india should leave happily then you have to think about banning RSS and sangh parivar. Zakir naik never done anything so that hindus and muslim divide. He always tried to unite all religion. I think you have not listened to any of his speeches. My sincere request with you is to first listen his all complete speeches. Then come to conclusion.
Please watch the below videos. It is available in Youtube
1.Similarities between Hinduism and Islam
2.Similarities between Islam and Christianity
3.Does God Exits
4.Is terrorism a muslim monopoly
Hope after watching the above you can change your thinking from negative to positive .
Over all this is a political game with the backing of rss communal group.
Started to target peace loving INDIANS and Mr. ZN is on top of their list.
There is many more to come from religious leader to business man;social worker; leading person etc.
Instead of 5 years high court need to ban for life time... so that everyone can leave happily in India
ZN is scared..he will not come back to india.. if he was Innocent he could have came back long back ago...
Add new comment