Diet sodas might not raise diabetes risk

November 16, 2016

Nov 16: Drinking colas and other sugary drinks is tied to an increased risk of so-called pre-diabetes, a precursor to full-blown disease, but diet soda is not, a recent study suggests.

dietPrevious studies on the link between diet sodas and diabetes have been mixed; some research pointing to a potential connection has suggested this relationship may be explained at least in part by soda drinkers being overweight or obese.

In the current study, however, adults who routinely consumed at least one can of soda or other sugar-sweetened beverages a day were 46 percent more likely to develop elevated blood sugar levels than people who rarely or never drink cola.

“Emphasis should be placed on substituting sugar-sweetened beverages with water, unsweetened teas, or coffee,” said senior study author Nicola McKeown, a nutrition researcher at Tufts University in Boston.

“For daily consumers of sugary drinks, kicking the habit may be a difficult challenge, and incorporating an occasional diet soda, while increasing fluids from other sources, may be the best strategy to ultimately remove sugar-sweetened beverages from the diet,” McKeown added by email.

Globally, about one in nine adults have diabetes, and the disease will be the seventh leading cause of death by 2030, according to the World Health Organization. Most of these people have Type 2, or adult-onset, diabetes, which happens when the body can't properly use or make enough of the hormone insulin to convert blood sugar into energy.

People with blood sugar levels that are slightly elevated, but not high enough for a diabetes diagnosis, are sometimes described as having “pre-diabetes” because many will go on to develop diabetes. In the current study, researchers examined data collected on 1,685 middle-aged adults over about 14 years.

At the start of the study, none of the participants had diabetes or pre-diabetes. They were 52 years old on average and typically overweight.

Participants completed questionnaires detailing what they ate and drank during the study period. Sugar-sweetened beverages were defined as colas and other carbonated beverages, as well as drinks such as lemonade and fruit punch. This didn’t include fruit juice.

People who drank the most sodas – typically around six 12-ounce cans a week – had a much greater risk of developing elevated blood sugar levels than other participants after adjusting for factors such as age, gender and weight, researchers report in the Journal of Nutrition.

Higher consumption of soda and other sugar-sweetened beverages was also associated with insulin resistance, a reduced ability to respond to the hormone insulin that is another risk factor for developing diabetes.

Even after accounting for changes in weight and other aspects of diet, the relationships between sugar-sweetened beverages and these metabolic risk factors for diabetes persisted.

Diet soda intake—defined as low-calorie cola or other carbonated low-calorie beverages— was not associated with elevated blood sugar or insulin resistance.

The study doesn’t prove soda or sugary drinks cause diabetes.

Another limitation of the study is that participants may not be representative of a typical U.S. adult, the authors note. People in the study were mostly white, middle aged and more likely to be women. They also tended not to be as overweight or thick around the middle as many U.S. adults, the authors point out.

Because pre-diabetic elevated blood sugar can often be reversed before it advances to full-blown disease, the findings suggest it makes sense for people to avoid regular sodas to minimize their risk of developing diabetes, the researchers conclude.

“Sugar sweetened beverages have been shown to increase weight gain and risk of diabetes – including prediabetes,” Laura Rosella, a public health researcher at the University of Toronto who wasn’t involved in the study, said by email.

The current study findings add to a large body of evidence suggesting that the sugar and calories in soda can contribute to the risk of obesity and diabetes, noted Dr. Robert Cohen, a researcher at the University of Cincinnati College of Medicine who wasn’t involved in the study.

“I wouldn’t necessarily seek out diet drinks but the choice of non-calorie containing diet drinks is not associated with further insulin resistance or pre-diabetes in the way that calorie containing drinks are,” Cohen said by email.

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May 17,2020

Geneva, May 17: Spraying disinfectant on the streets, as practised in some countries, does not eliminate the new coronavirus and even poses a health risk, the World Health Organization (WHO) warned on Saturday.

In a document on cleaning and disinfecting surfaces as part of the response to the virus, the WHO says spraying can be ineffective. "Spraying or fumigation of outdoor spaces, such as streets or marketplaces, is... not recommended to kill the Covid-19 virus or other pathogens because disinfectant is inactivated by dirt and debris," explains the WHO.

"Even in the absence of organic matter, chemical spraying is unlikely to adequately cover all surfaces for the duration of the required contact time needed to inactivate pathogens." The WHO said that streets and pavements are not considered as "reservoirs of infection" of Covid-19, adding that spraying disinfectants, even outside, can be "dangerous for human health".

The document also stresses that spraying individuals with disinfectants is "not recommended under any circumstances".

"This could be physically and psychologically harmful and would not reduce an infected person's ability to spread the virus through droplets or contact," said the document.

Spraying chlorine or other toxic chemicals on people can cause eye and skin irritation, bronchospasm and gastrointestinal effects, it adds.

The organisation is also warning against the systematic spraying and fumigating of disinfectants on to surfaces in indoor spaces, citing a study that has shown it to be ineffective outside direct spraying areas.

"If disinfectants are to be applied, this should be done with a cloth or wipe that has been soaked in disinfectant," it says.

The SARS-CoV-2 virus, the cause of the pandemic that has killed more than 300,000 people worldwide since its appearance in late December in China, can attach itself to surfaces and objects.

However, no precise information is currently available for the period during which the viruses remain infectious on the various surfaces.

Studies have shown that the virus can stay on several types of surfaces for several days. However, these maximum durations are only theoretical because they are recorded under laboratory conditions and should be "interpreted with caution" in the real-world environment.

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Agencies
January 12,2020

Washington D.C., Jan 12: Disruption in one night's sleep can lead to getting Alzheimer's disease, a recent study has stated.

The interruption in the sound sleep for a single night aggravates the level of tau protein in any young male's body, thus gives rise to the chances of developing the disease.

According to CNN, the report was published on Wednesday in neurology, the medical journal of the American Academy of Neurology.

"Our study focuses on the fact that even in young, healthy individuals, missing one night of sleep increases the level of tau in blood suggesting that over time, such sleep deprivation could possibly have detrimental effects," says study author Dr Jonathan Cedernaes, a neurologist at Uppsala University in Sweden.

As defined by the Alzheimer's Association, tau is the name of a protein that helps in stabilizing the internal structure of the brain's nerve cells. An abnormal build-up of tau protein in the body can end up in causing interior cells to fall apart and eventually developing Alzheimer's.

"When you get more of that deep sleep and you get the REM sleep in the normal amounts, that improves clearance of abnormal proteins which we think is good," said Mayo Clinic neurologist Dr Donn Dexter, not the study author but a fellow of the American Academy of Neurology.

Earlier studies have also shown that getting deprived of sleep can allow higher tau development and accumulation. Thus that poor sleep can hasten the development of cognitive issues.

Researchers caution that the study is small and inconclusive, and acknowledged they were not able to determine what the increased levels might mean.

"This study raises more questions than answers," agreed Dexter on a concluding note, sharing, "What this is telling us is that we have to dig more deeply. Despite something we do for a third of our lives, we know so little about sleep and we're learning every day, particularly when it comes to sleep and dementia."

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January 11,2020

Europe, Jan 11: Researchers have revealed the people who drink tea at least three times a week have healthy years of life and longer life expectancy.

The research was published in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC).

Dr Xinyan Wang, who is the author of the study, said: "Habitual tea consumption is associated with lower risks of cardiovascular disease and all-cause death. The favourable health effects are the most robust for green tea and for long-term habitual tea drinkers."
The analysis that was conducted included about 100,902 participants of the China-PAR project2 with no history of heart attack, stroke, or cancer.

Participants were classified into two groups: Habitual tea drinkers and never or non-habitual tea drinkers and followed-up for a median of 7.3 years.

The analyses estimated that 50-year-old habitual tea drinkers would develop coronary heart disease and stroke 1.41 years later and live 1.26 years longer than those who never or seldom drank tea. Compared with never or non-habitual tea drinkers, the habitual tea consumers had a 20 per cent lower risk of incident heart disease and stroke, 22 per cent lower risk of fatal heart disease and stroke, and 15 per cent decreased risk of all-cause death.

The potential influence of changes in tea drinking behaviour was suspected in a subset of 14,081 participants with assessments at two-time points. The average duration between the two surveys was 8.2 years, and the median follow-up after the second survey was 5.3 years.

Habitual tea drinkers who maintained their habit in both surveys had a 39 per cent lower risk of incident heart disease and stroke, 56 per cent lower risk of fatal heart disease and stroke, and 29 per cent decreased risk of all-cause death compared to consistent never or non-habitual tea drinkers.

Senior author Dr Dongfeng Gu said: "The protective effects of tea were most pronounced among the consistent habitual tea drinking group. Mechanism studies have suggested that the main bioactive compounds in tea, namely polyphenols, are not stored in the body long-term. Thus, frequent tea intake over an extended period may be necessary for the cardioprotective effect."

In a subanalysis by type of tea, drinking green tea was linked with approximately 25 per cent lower risks for incident heart disease and stroke, fatal heart disease and stroke, and all-cause death. However, no significant associations were observed for black tea.
Dr Gu noted that a preference for green tea is unique to East Asia.

Two factors may be at play. First, green tea is a rich source of polyphenols which protect against cardiovascular disease and its risk factors including high blood pressure and dyslipidaemia. Black tea is fully fermented and during this process, polyphenols are oxidised into pigments and may lose their antioxidant effects. Second, black tea is often served with milk, which previous research has shown may counteract the favourable health effects of tea on vascular function.

Gender-specific analyses showed that the protective effects of habitual tea consumption were pronounced and robust across different outcomes for men, but only modest for women. Dr Wang said: "One reason might be that 48 per cent of men were habitual tea consumers compared to just 20 per cent of women. Secondly, women had a much lower incidence of, and mortality from, heart disease and stroke. These differences made it more likely to find statistically significant results among men."

She said: "The China-PAR project is ongoing, and with more person-years of follow-up among women the associations may become more pronounced."

In conclusion, the authors have found that randomised trials are required to validate the results and to illustrate nutritional guidelines and advice for lifestyle.

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