Dozens of cattle starved to death in goshala; hundreds in critical condition

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Jun 24: About 8,48,203 students will appear in the Secondary School Leaving Certificate (SSLC) examination tomorrow, i.e., June 24, said Karnataka Health Minister B Sriramulu on Wednesday.

Students have been advised to report to the examination centre three-hour before the commencement of the examination i.e., at 07:30 am. The examination will commence at 10:30 am.

Early entry to the centres will also help maintain social distancing that is very much essential during the pandemic, minister for primary and secondary education S Suresh Kumar said.

"SSLC exams to take place tomorrow. About 8,48,203 students will write the exam. Social distancing needs to be followed and the mask should be used. Minister of Education and I have already held a lot of meetings. Students from containment zones will be carefully handled," said Sriramulu.

Commenting upon the situation arising in the state due to COVID-19, Sriramulu said, "There is a panel of experts to decide about lockdown. There has been an opinion that the COVID-19 test should be increased. Workers, traders, and others should be categorised in 15 categories and tests must be conducted," he added.

Sriramulu further said that there will be a meeting of task force on the coming Monday.

"All the issues will be brought to the notice of the Chief Minister at the task force meeting, then CM will take a call on what needs to be done," he said.

Meanwhile, Suresh Kumar, Minister of Education inspected the schools and places where SSLC exams will be held.

Earlier Karnataka Education Minister S Suresh Kumar had announced that SSLC examinations, which were stayed in view of the coronavirus pandemic, will be conducted 'between June 25 and July 4' in the state.

According to the Union Health Ministry, Karnataka has 9,721 COVID-19 cases including 150 fatalities.

Mangaluru, Jul 4: Normal life was thrown out of gear as heavy rain under the influence of South East Monsoon started lashing coastal districts of Karnataka including Dakshina Kannada on Saturday.

The heavy rain is likely to continue till July 7, according to the meteorological experts. 

The water level in Netravati river is increasing and district administration has warned the people living in the low lying areas and has asked them to move to safer places.

Owing to lack of storm water drains, water logging of the roads inconvenienced the motorists at KS Rao Road, Pumpwell, Bejai, and other areas. 

The Met department sounded warning for fishermen not to venture into the sea observing that strong winds with speed reaching 50-60 kmph are likely to prevail over Southwest and West Central Arabian Sea till July 5.