Dr Kafeel Khan who saved hundreds of infants sacked amid Yogi’s visit

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, July 13: The Karnataka government today announced the cancellation of I PUC supplementary examinations across the state. 

Primary and Secondary Education minister S Suresh Kumar announced that the government took the decision in the wake of rising cases of Covid-19 and re-introduction of the lockdown. According to sources in the education department, as many as 60,000 students were supposed to appear for the examination.

Previously, the state government had decided to hold these exams at the college level in every district and publish the results by 30 July. However, the government has withdrawn even that arrangement and completely cancelled the exams. 

According to the minister, all the students who failed in the I PUC examination, shall also be promoted to II PUC. "The students who have attended all the subjects but unable to pass the exams will also be promoted to the next class," Suresh Kumar said.

However, those who missed out on the exams due to health reasons or failed in the examinations will be given a small test at the time of commencing classes for II PUC to assess their learning ability at the college level, according to the minister. "Only those students who missed out on the examination due to shortage of attendance will not be promoted to the next class," Suresh Kumar clarified.

Bengaluru,  Mar 26: The nationwide lockdown in the view of coronavirus outbreak has driven some people to the edge. In Karnataka, within less than 24 hours, two cases of people creating trouble for police personnel have come to light.

On Wednesday, a middle-aged man was shot in his leg by the police after he tried to assault two police constables of Sanjaynagar police station. The police constables were identified as Manjunatha and Basavararaju.
The accused reportedly breached the check post at Bhoopasandra. He and his friends were over-speeding and performing stunts on bikes. When the policemen tried to secure them after giving them a chase, they attacked the cops.

When they were taken into custody, one of them again tried to escape and hurled stones and bricks on the cops. In order to prevent further assault, the police then fired two rounds – one in the air and the second one on his left leg.