Drug menace spreading to rural areas in DK thanks to Cong leaders: Kateel

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangalore, Mar 11: There everybody busy in hailing ‘Padmashree’ Harekala Hajabba. They wondered how an orange seller turned into an educationist with his grit and high objectives. However, the center of attraction- Harekala Hajabba was thinking how to transfer a cheque of rupees one lakh to a current account of his school!

Dakshina Kannada District Kannada and Culture Department had an interaction program with Harekala Hajabba at Ravindra Kalabhavana of University College Mangaluru on Wednesday. The department, as well as Dakshina Kannada District Bus Owners’ Association felicitated the achiever. They also honored Hajabba with a cash of rupees one lakh. Instantly, the man decided to utilize the amount for his school! 

In his address, Guruvappa N T Balepuni, who introduced Harekala Hajabba to society opined that with his simplicity, humbleness, moreover his service without any expectation, Hajabba is being respected everywhere. Though he is an illiterate, three universities have made his life as lessons for students. “He has kept around Rs 50-55 lakh, including his award money for the development of school. January 25, the day on which ‘Padmashree’ award has been declared to Hajabba is a memorable day for me too,” he added. 

Dakshina Kannada District Bus Owners’ Association President Dinram Alva and former president Jayaram Shekha opined that there is lot to learn from Hajabba and he is a model for the society. Recalling his old- harsher days, Hajabba said, “Parents should make mind to save government schools. A literate can achieve anything, he can lead the society,” he said and called upon for the communal harmony. 

Presiding over the function, Principal Dr. Uday Kumar M A said that Harekala Hajabba is best example how a pure-hearted man achieves any height, simplicity can make someone so rich. In his welcome speech District Kannada and Culture Department Deputy director Rajesh G, depicted Hajabba as ‘modern time Mahatma Gandhi’. Economics PG Coordinator Dr. Jayavantha Nayak and M.Com Coordinator Dr. Abobakkar Siddiq were present on the occasion.

Bengaluru, May 20: 63 more COVID-19 cases have been reported from Karnataka, taking the total number of coronavirus cases in the state to 1,458 on Wednesday, said the state Health Department.

The total number of cases includes, 864 active cases and 41 deaths (one due to non-COVID cause), it added.

Total 10 people have been discharged today while 553 persons have been discharged so far.