Emission from diesel engines linked to premature death

Agencies
February 27, 2019

US, Feb 27: Some 385,000 people worldwide died prematurely in 2015 from air pollution caused by vehicle exhaust emissions, a US study found Wednesday, which singled out diesel engines as the main culprit.

Diesel vehicles were responsible for 47 percent of the deaths, it said, but the figure jumped as high as 66 percent in France, Germany, Italy and India where diesels make up a large proportion of cars on the road.

The study was carried out by researchers from the International Council on Clean Transportation (ICCT), the non-governmental group that blew the whistle on Volkswagen's "dieselgate" emissions cheating scandal in 2015 and two US universities.

"The high public health burden of diesel vehicles in Europe underscores the need for world-class emissions standards to be accompanied by robust compliance and enforcement," said ICCT co-author Joshua Miller, calling for urgent action to replace high-emissions vehicles.

Researchers studied the impact of fuel emissions from diesel and non-diesel vehicles, as well as agricultural and construction machinery and their impact on our health. They found that the global transportation sector was responsible for 11 percent of the 3.4 million premature deaths annually attributed to pollution from fine particles (PM2.5) and ground-level ozone exposure.

The cost of the health burden caused by transport pollution, which has been linked to lung and heart diseases, strokes and diabetes, added up to $1 trillion (880 billion euros) in 2015, they said.

In China alone, some 114,000 people were killed by vehicle exhausts that year, but that still only accounted for just over 10 percent of all deaths linked to air pollution there.

The United States saw 22,000 deaths from transport pollution, of which 43 percent were linked to diesels. India meanwhile recorded 74,000 premature deaths from vehicle exhausts, compared with 13,000 in Germany, 7,800 in Italy and 6,400 in France.

Relatively speaking however, the picture was worst in Germany with 17 premature deaths blamed on transport pollution per 100,000 residents, three times higher than the global average.

Milan, Turin, Stuttgart, Kiev, Cologne, Berlin and London were among the deadliest cities in terms of transport pollution, the researchers noted. The authors cautioned that their estimates were "conservative" as their study did not take into account all types of harmful emissions or pollution-linked diseases. "Consideration of these impacts would likely increase the estimate of health impacts from vehicle exhaust emissions," they warned.

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News Network
July 10,2020

Toronto, Jul 10: Pasteurising breast milk at 62.5 degrees Celsius for 30 minutes inactivates the SARS-CoV-2 virus that causes Covid-19, making it safe for consumption by babies, a study claims.

According to the research published in the Canadian Medical Association Journal, current advice for women with Covid-19 is to continue to breastfeed their own infants.

In Canada, it is standard care to provide pasteurised breast milk to very-low-birth-weight babies in hospital until their own mother's milk supply is adequate, the researchers said.

"In the event that a woman who is Covid-19-positive donates human milk that contains SARS-CoV-2, whether by transmission through the mammary gland or by contamination through respiratory droplets, skin, breast pumps and milk containers, this method of pasteurisation renders milk safe for consumption," said Sharon Unger, a professor at the University of Toronto in Canada.

The Holder method, a technique used to pasteurise milk in all Canadian milk banks at 62.5 degrees Celsius for 30 minutes, is effective at neutralising viruses such as HIV, hepatitis and others that are known to be transmitted through human milk, the researchers said.

In the latest study, the researchers spiked human breast milk with a viral load of SARS-CoV-2 and tested samples that either sat at room temperature for 30 minutes or were warmed to 62.5 degrees Celsius for 30 minutes.

They then measured for active virus, finding that the virus in the pasteurised milk was inactivated after heating.

More than 650 human breast milk banks around the world use the Holder method to ensure a safe supply of milk for vulnerable infants, the researchers said.

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Agencies
February 23,2020

Los Angeles, Feb 23: According to researchers, if administered quickly, a common medication that reduces bleeding could be a treatment for bleeding stroke.

The Spot Sign and Tranexamic Acid on Preventing ICH Growth - Australasia Trial (STOP-AUST) was a multicenter, prospective, randomized, double-blind, placebo-controlled, phase 2 clinical trial using the antifibrinolytic agent tranexamic acid in people with intracerebral hemorrhage (ICH).

ICH is a severe form of acute stroke with few treatment options.

Tranexamic acid is currently used to treat or prevent excessive blood loss from trauma, surgery, tooth removal, nosebleeds and heavy menstruation. For this study, one hundred patients with active brain bleeding were given either intravenous tranexamic acid or placebo within 4.5 hours of symptom onset.

Researchers analyzed brain CT scans taken during the 24-hour period after treatment with tranexamic acid or placebo.

Researchers found a trend towards reduced hemorrhage expansion in the group treated with tranexamic acid, especially in those treated within 3 hours of the brain bleed. However, this trend was not statistically significant. The finding was consistent with previous research using the medication.

"Further trials using tranexamic acid are ongoing and focusing on ultra-early treatment - within 2 hours. 

This is where the greatest opportunity for intervention appears to be. Tranexamic acid is inexpensive, safe and widely available. Our results and others provide great impetus for further, focused research using this treatment," Nawaf Yassi said.

Larger trials focused on patient outcomes are required for this therapy to enter routine clinical practice.

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