Endosulfan claims teenage girl’s life in DK; she was a brilliant student, says family

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Bengaluru, Apr 18: Private unaided schools in the state that were demanding fees from parents in the name of online classes and taking online admissions will face action under Section 3 of the Epidemic Diseases Act 1897, the Karnataka government said.

The Department of Public Instructions has warned school management of action against such educational institutes if they violate the rules. Following complaints from several parents and also from private school management associations, Minister for Primary and Secondary Education S Suresh Kumar discussed the issue with officials from the department during a recent meeting and directed them to initiate action against such academies.

In a guideline issued on Saturday, the department said, "Schools can conduct online classes. But are not permitted to collect the fee from parents until further orders from the department."

Mangaluru, Jun 28: The patience and presence of mind exhibited by the family members of youth covid-19 victim thwarted the attempt by a few miscreants to create communal disharmony in the coastal city today.

A 31-year-old youth from Idya in Surathkal, who was under treatment for covid-19 at designated Wenlock Hospital in the city, passed away last night. 

Even though there is a Muslim graveyard under the jurisdiction of Idya mosque, it was waterlogged due to heavy rains. 

Hence, the Idya mosque management had obtained permission from Mangaluru’s Bolar mosque management to bury the mortal remains of the youth in Bolar graveyard. 

All necessary arrangements were made at the Bolar graveyard for the burial this morning. Meanwhile, a few residents of Bolar belonging to another community staged a protest against bringing covid-19 victim’s mortal remains to Bolar.

Mohammad Husain, general secretary of Bolar mosque, said that the family members of the departed youth exhibited their presence of mind and urged the Muslims of Bolar to preserve communal harmony.

“The Bolar mosque committee had given green signal for the burial and all arrangements were made. Meanwhile, a few people staged protest and warned us against burying the covid-19 victim’s body. When the aggrieved family members came to know this, they immediately cancelled the plan,” he said. 

“The aggrieved family requested us to uphold communal amity and co-existence. They decided to bury the body in Idya itself. Then the protesters also returned,” he said.

Burial in Bolar after DC’s intervention

When the mortal remains were being taken towards Surathkal in the ambulance, the Deputy Commissioner of Dakshina Kannada ordered the authorities concerned to take a U-turn and bring back mortal remains to Bolar.  

The DC said it was wrong to take the mortal remains to another place after making all necessary armaments in Bolar graveyard. In order to pacify the porters it was decided to dig another grave on the other side of the graveyard, sources said.