England 'mistakenly' awarded extra run in final: Simon Taufel

Beijing/Zurich, Mar 4: China has approved the use of Swiss drugmaker Roche's anti-inflammation drug Actemra for patients who develop severe complications from the coronavirus as it urgently hunts for new ways to combat the deadly infection that is spreading worldwide.

China is hoping that some older drugs could stop severe cytokine release syndrome (CRS), or cytokine storms, an overreaction of the immune system which is considered a major factor behind catastrophic organ failure and death in some coronavirus patients.

Actemra, a biologic drug approved in 2010 in the United States for rheumatoid arthritis (RA), inhibits high Interleukin 6 (IL-6) protein levels that drive some inflammatory diseases.

China's National Health Commission said in treatment guidelines published online on Wednesday that Actemra can now be used to treat coronavirus patients with serious lung damage and high IL-6 levels.

Separately, researchers in the country are testing Actemra, known generically as tocilizumab, in a clinical trial expected to include 188 coronavirus patients and running until May 10.

Roche, which donated 14 million yuan ($2.02 million) worth of Actemra during February, said the trial was initiated independently by a third party with the aim of exploring the efficacy and safety of the drug in coronavirus patients with CRS.

It added that there was currently no published clinical trial data on the drug's safety or efficacy against the virus.

More than 3,000 people have died and 93,000 have been infected by the novel coronavirus thought to have originated in Wuhan, China, before spreading to around 90 countries including the United States, Italy, Switzerland, France and Germany.

The Swiss company, for which China is its No. 2 market behind the United States, also makes diagnostic gear to detect the coronavirus.

Since Actemra's approval a decade ago, it has become a go-to drug against other inflammatory conditions, including cytokine storms in cancer patients receiving cell therapies from Novartis and Gilead Sciences.

In 2012 it helped save the life of a young U.S. girl, the first child to be treated for leukaemia with Novatis' Kymriah, from a post-treatment rush of IL-6.

Priced at between $20-30,000 annually for RA according to SSR Health, Roche's medicine is also used for rare juvenile arthritis and giant cell arteritis, or inflammation of the blood vessels.

Kingston, Jun 10: "Enough is enough", said West Indies all-rounder Dwayne Bravo as he opened up on the raging issue of racism and called for "respect and equality" for black people, who have faced discrimination for years.

Bravo joined the likes of his former captain Darren Sammy and Chris Gayle in denouncing racism in the wake of African-American George Floyd's killing at the hands of a white police officer in the USA.

"It's sad to see what's going on around the world. As a black man, we know the history of what black people have been through. We never ask for revenge, we ask for equality and respect. That's it," Bravo told former Zimbabwe cricketer Pommie Mbangwa in an Instagram live chat on Tuesday.

"We give respect to others. Why is it that we are facing this over and over? Now enough is enough. We just want equality. We don't want revenge, war.

"We just want respect. We share love and appreciate people for who they are. That's what is most important."

The 36-year-old, who has played 40 Tests, 164 ODIs and 71 T20Is for West Indies, said he wants the world to know that they are powerful and beautiful people and gave the example of greats such as Nelson Mandela, Muhammad Ali, Michael Jordan.

"I just want our brothers and sisters to know that we are powerful and beautiful. And at the end of the day, you look at some of the greats of the world, whether it is Nelson Mandela, Muhammad Ali, Michael Jordan we have had leaders who paved the way for us," he said.

Two-time T20 World Cup-winning captain Sammy had earlier alleged that a racist nickname was used to address him during his IPL stint with Sunrisers Hyderabad and demanded an apology.

Sammy said he was called 'Kalu' while he was in India. 'Kalu' is a derogatory word to describe black people.

Gayle, who too plays in the IPL, took to Twitter to back Sammy, saying that racism does exist in cricket.

"It's never too late to fight for the right cause or what you've experienced over the years! So much more to your story, @darensammy88. Like I said, it's in the game!!," Gayle tweeted.

Jul 21: The tickets sold for the now-postponed ICC T20 World Cup will remain valid if Australia hosts the edition in 2021 instead of India.

In case the event is shifted to 2022, all ticket-holders will be entitled to a full refund, the ICC stated on its website on Monday night after postponing the mega-event this year due to the Covid-19 pandemic.

The tournament was to be held in October-November but will now be conducted later because of the pandemic.

The ICC has not yet announced which country will host which edition as there are operational issues that both the Indian and Australian cricket Boards need to sort out.

The world body had opened ticket booking through its ticketing partners and a significant number was already sold.

"Ticket holders are welcome to retain their tickets, noting, if Australia hosts in 2021, tickets will remain valid for fans who have already bought and will be automatically updated to reflect the new dates.

"If Australia hosts in 2022, for tickets already bought a full refund will be processed automatically," ICC stated in a series of FAQs.

Fans can retain their tickets until a date is confirmed for the event.

Refund requests can be made until December 15 and they will be processed within 30 days after an online submission.

The hospitality package will also remain valid for the 2021 fixtures.