May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Your agenda in all election is " We will build Ram Mandir" if we elected to assembly. Now Central is with BJP hand, UP is with BJP hand then what is the issue? Why again and again saying we will build Ram Mandir - Ram Mandir every now and then. Road is free and why dont you take steps to build the temple and finish the issue?
Dear Non Muslim brothers and sisters, believe it or not - These so called politicians will never build Ram Mandir or whatsoever. This is the main Muddah for their election campain. Actually we the voters are fool and fighting each other (Hindu & Muslim), killing , looting innocents etc etc. - Finally who will benefit? These politicians and who is the looser - WE
Dear All - Please think about the development of our state, country and cast your valuable vote to the right candidate who may contribute to the development of our state/country. In this era Mandir-Masjid is not the issue - Issue is development, education, job, food etc etc.
The problem is BALATKARI JANWAR PATRY (BJP), Modi and Amit shah style of running the government on Hitler style has already filled the gandu rashtra people with poison in their brains to send Muslims out of India. This is the real problem. Gandus want their gandu rashtra at any cost now. Arab Muslims ruled India for 900 years and enriched the country with coffee, silk etc. Then British came and looted the country. Then these BJP and RSS are gifted with the divide and rule formula from British. They are now just following the same old formula to eat up whatever is left in the country. All this making hindu rashtra etc is a drama.
Comparing to Japan and other countries India is quite behind, because their aim is development, whereas our aim is Mandir/Masjid and religion. If India continues the same theory, India will never develop. These politicians are taking India on wrong direction.
Tippu is dead , shivaji also is dead. Why not worry about poor people like us who are still alive? We have enough masjid to pray , Allah will accept our prayers from any masjid, plz dont worry about that. Kindly finish the ram mandir as soon as possible. After all this done, kindly focus on jobs, roads, farmers, water, food, social services etc. i hope this is very simple english so u and your like minded friends can understand.
Thanks
kachda chaddi,,
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