Germany’s anti-Islam political party’s leader embraces Islam

Canadian researchers are developing a DNA vaccine for SARS-CoV-2, the coronavirus that causes COVID-19 and has currently infected nearly 5,00,000 people worldwide and crippled the global economy.

Entos Pharmaceuticals, a health-care biotechnology company headed by a University of Alberta researchers, develop new therapeutic compounds using the company's proprietary drug-delivery platform and has begun manufacturing vaccine candidates against the novel coronavirus.

"Given the urgency of the situation, we can have a lead candidate vaccine within two months. Once we have that it's a race to get it into clinical trials," said John Lewis, CEO of Entos and a Professor at the University of Alberta in Canada.

Lewis said in comparison to a traditional vaccine, DNA-based vaccines hold several advantages.

Nucleic acids are introduced directly into the patient's own cells, causing them to make pieces of the virus--tricking the immune system into mounting a response without the full virus actually being present, the researcher said.

According to the company, the approach is recognised as being easier to move into large-scale manufacturing, offers improved vaccine stability and works without needing an infectious agent.

In the current absence of a vaccine for COVID-19, several companies around the world are mounting efforts to begin similar work.

The first clinical trial using a DNA-based vaccine developed by Moderna Inc.in the US on March 13.

Their approach allows for antibodies to be made in the human trial volunteers against a specific protein on the surface of the coronavirus that lets the virus enter human cells.

The hope is that the antibodies will stop the interaction.

Though this approach is designed to be effective against COVID-19 specifically, Lewis said Entos is taking a different tack.

The company plans to use plasmid DNA to amplify the production of key coronavirus surface and structural proteins with each injection, with an eye to the bigger picture.

"Many of the structural proteins in the virus are pretty well conserved across all the coronaviruses, including SARS and MERS," said Lewis.

"We're hoping that if we express more of the structural proteins that are common to most coronaviruses, we can inhibit the current COVID-19, and also potentially protect against all coronaviruses both past and future," Lewis added.

To move the project forward quickly, the company is seeking financial support from both provincial and federal levels of government.

"We have the opportunity to save a lot of lives, and I think it's really upon us and governments to find solutions for that," Lewis said.

Chennai, Feb 20: Three people, including an assistant director were killed and 9 others injured when a crane used for the shooting of “actor Kamal Haasan starrer “Indian 2” film crashed down at Nazarathpet near Poonamallee here late on Wednesday night.

Police said the accident occurred when a group of workers were engaged in erecting a set for a scene at EVP film city, private studio. As the crane crashed down, a heavy-duty light stand that was mounted on it also fell on the workers.

Mr Haasan and the film director S.Shankar escaped unhurt in the accident.

The deceased were identified as Krishna (34), an assistant director of the film, Madhu (29) and Chandran (60), who was part of the catering team.

Tamil Nadu Fire and Rescue Services personnel, along with a fire tender from Irungattukottai rushed to the spot and retrieved the bodies from the spot.

Mr Haasan, who was at the accident spot, also helped to transport the injured people to a private hospital near Poonamallee.

The bodies were sent to the Government General Hospital for post-mortem.

The Nazarathpet police have filed a case and are investigating the cause of the accident.

Meanwhile, Mr.Haasan condoled the death of three people during the film shoot. “The accident is the most horrific I have seen in my film career. I have lost three colleagues, but my pain pales in comparison to the grief of those who have lost their loved ones.

My deepest sympathies to them, he tweeted.

The Lyca productions also expressed condolences over the tragic accident. “We are extremely saddened with the unfortunate accident happened at the sets of Indian 2. We have lost three of our most hardworking technicians, it tweeted.

Balochistan, May 1: Sajid Hussain, Editor-in-Chief of Balochistan Times, has been found dead in a Swedish town, the police have confirmed.

The Swedish police informed his family on Thursday night that they discovered his body from a river in Uppsala, The Times reported.
The Baloch journalist had been missing from the Swedish city since March 2 this year.

Sajid, 39, left Pakistan in 2012 and had been living as a refugee in Sweden since 2017. He wrote extensively on the suffering of the Balochis at the hands of the Pakistani military establishment.

His work often got him into trouble as the authorities did not like his reporting of Balochistan's forbidden stories, the reason he had to leave and live in exile.

The Baloch journalist was found dead two months after he went missing in Sweden.
Sajid left Pakistan because of security threats from Pakistan Army and its intelligence service ISI.

The spokesperson of the Baloch National Movement, Hammal Haider told news agency: "We are deeply saddened by the demise of prominent Baloch intellectual and writer Sajid Hussain."
"His death is indeed a loss of a great mind for the people of Balochistan. Due to his straightforwardness, he was loved among all journalistic, literary and political circles," added Haider.

"After this incident, we have serious concerns about our members and other Baloch refugees living in the West," he said.