Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
RIP ...plis some one filled the on naga devata ... I think he retrun to naga loka ....
Yaar please call the creator as god....not creation....koi bhi jaati ho...don't take the characters of valmiki tales and call all the characters in it as GOD....keep it device...not every Pathar kutta billli saamp GO ect
Hinduism is commonly perceived as a polytheistic religion, Indeed most hindus would attest to this, by professing belief in multiple gods. while some hindus believe in the existence of 3 gods. some believe in thousands of gods and some other in thirty three crore i.e 330 million gods how ever learned hindus who is well versed in scriptures insist that a hindu should believe in one god.
The major difference between hindu and muslim is perception of god is common. Hindu belief in philosophy of pantheism. pantheism considers everything living and non living. to be divine and sacred.the common hindu therefore consider everything as god.he consider sun moon snake monkey etc and even human being as manifestations of god!
Islam on the contrary, exhorts man to consider himself and his surroundings as example divine creation rather then as divinity itself. Muslim therefore believe that everything is God's i.e the word god with an apostrophe 's'. In other words muslim believe that everything belong to god. The tree snake monkey etcin the universe belong to god.
Thus the major difference between the Hindu and Muslim Beliefs is the difference of apostrophe 's'. The Hindu says everything is god. The Muslim says everything is God's. Therefore 'WORSHIP THE CREATOR NOT HIS CREATIONS.
How can a god bite and kill his creations?
Yeh Wrong No. hai, Read your authentic scriptures and ponder on it.
RIP!
Superstition belief....snake does not spare anyone....but it should have...cant play with it....
we cannot blame the snake here because
girls know that is god as per hindhu culture but
snake dont know that it is god
Cow, buffalo, Rat, Elephant, Crow, Monkey, Donkey, Snake.. What next? Mooka praani galella dewara? worship the creator not creations! and specially not animals..
Indians are foolish, this happens only in India they do not know what to worship linga, snake, monkey, donkey, pig etc.....
Yes to cover their cunning and so called deva bhakti, some will start to blame that lady. Punishment from Naag devtha and they will continue these bling practice.
karana rao, Where is naga loka?
Whatever may be the reason, we lost a precious life. Pray for God's mercy on the poor family.
Snake is not God or it will not take you to God. Worship the creator and not his creation.
this is called mooda nambike and she deserve for it.
she will directly go to nagaloka, lucky girl.
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