May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
"Whether it is named qabristan (graveyard) or shamshaan (crematoriums), nobody needs to be buried. There are 2-2.5 crore Hindu saints in this country who should have a memorial after their death. That will require land. There are 20 crore Muslims, all of them need a grave. Where is the land in Hindustan?" Maharaj said today.
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First cremate this dog then bury to ensure he is fully dead, otherwise his atma may roam everywhere to make mischief activity by joining sanghi. One Atma is already there in country's top post.
real issue we are facing same problem in mangalore need to improvement
This fool needs immedaite treatment before he goes 100 percent mad and runs in the street without clothes. I hope the mother who gave birth to this fool is repenting for the mistake. She is also might be cursing him. He is a waste to our land and his chapter should be closed at the earliest. PM MOdi is silent on the remarks made by his chela. PM himself gave incorrect and illogic and irresponsble statement. Being a PM he should not have made such statement. I think Mukhtar naqwi and Shanawaz have agreed to sakshi maharge statement and given their consent to cremate their bodies after death.
How come these kind of funny and illiterates become MP ???? How funny he talks and if you check his history its shocking...
Barking dogs are not biting
The uneducated and unethical person
To correct him, he should be circimcised . He should be served with dogs, snakes in his daily food as it is done in Singapore...... If you want Hindu population, get married no of wives and produce children, But do not desert the wives like your Boss....
LOL, he thoughts INDIA means only Uttar Pradesh....
This guy surely gone mad!
Are Muslims responsible for all those 100 crore Hindu population.
Who let the dogs out....
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