Hat-trick victory for Nalin Kumar Kateel as Congress bites the dust in DK

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Kalaburagi, Mar 7: Congress and JDS MLAs are eagerly waiting to join BJP, said former minister and chairman of Nijasharana Ambigara Choudaiah Abhivradhi Nigama, Baburao Chinchansur, here on Friday.

Speaking at a press conference here, Baburao said if the BJP top brass gives a green signal to include MLAs of other parties, both Congress and JDS would be almost empty. Many leaders, including D K Shivakumar and G Parameshwara, won’t support Siddaramaiah and the former CM will have to find his own way in the coming days, he predicted. He said Congress will not be coming to power in Karnataka for the next 20 years, he said.

Chinchansur thanked Chief Minister B S Yediyurappa for providing Rs 50 crore for Nijasharana Ambigara Choudaiah Abhivrudhi Nigama in the budget. He also said that a delegation will be taken to New Delhi under the leadership of the CM, after the budget session, to pressure the Union government to include Koli community in ST category.

Bengaluru, Jun 6: Karnataka Chief Minister B S Yediyurappa on Saturday said hotels and restaurants would be allowed to re-open, but the precautionary measures laid down by the Centre against coronavirus were mandatory.

The Chief Minister on Friday held a meeting with the tourism and transport department, also stakeholders, regarding revival of tourism in the state.

Hotels associations and transport companies have said they would follow the guidelines issued by the government, an official press release said here.

The Karnataka government had said it would go by the Centre's direction on opening religious places of worship, shopping malls, hotels, restaurants and other hospitality services on June 8.

Buses, hotels and taxi owners association placed some demands at the meeting, the release said, adding that Yediyurappa informed them that he would examine their demands and take appropriate decisions.

The Chief Minister also released a handout regarding the guidelines that need to be followed as the tourism department is opening hotels, guest houses and tourist destinations.

Deputy Chief Minister Laxman Savadi, Tourism Minister C T Ravi and senior officials of the department participated in the meeting.

The government had, on Thursday, said safaris, trekking, jungle lodges and resorts in areas that fall outside the COVID-19 containment zones can re-open provided they adhere to social distancing, hygiene as issued by the governments.