Heart attack risk high with one cigarette a day: study

Agencies
January 25, 2018

Paris, Jan 25: Just one cigarette a day carries nearly half the risk for heart attack and stroke as smoking a full pack of 20, according to a large-scale study published Thursday.

"If someone smokes one cigarette instead of 20 per day, intuitively we'd think that the risk drops to 1/20, or five percent," said lead author Allan Hackshaw, a professor at University College London, whose paper analysed 141 previous studies.

"This seems to be the case for lung cancer, but is not true for heart attacks and stroke, where one cigarette per day carries around 50 percent of the risk of a pack a day," he told AFP.

Smokers should not be fooled, in other words, into thinking that a few cigarettes a day -- or even just one -- carries little or no long term harm, he added.

"Whilst it is great that smokers try to cut down -- and they should be positively encouraged to do so -- in order to get the big benefits on cardiovascular disease they need to quit completely," he said by email.

Tobacco kills about seven million people worldwide every year, according to the World Health Organization.

About two million of those deaths are due to cardiovascular disease, mainly coronary heart attacks and stroke.

Earlier research suggested that smoking a few cigarettes a day was linked to a higher-than-expected risk of heart disease, but findings were inconclusive.

To probe deeper, a team of scientists led by Hackshaw analysed the results of 141 studies, estimating the relative risk of one, five or 20 cigarettes a day.

They found that men who lit up once a day had 46 percent of the excess risk of heart disease associated with smoking a full pack a day, much higher than expected. For strokes, the excess risk was 41 percent.

For reasons that are not fully understood, the risk for women was somewhat smaller -- 31 and 34 percent, respectively.

"It could be a mixture of biological difference and differences in lifestyle," said Hackshaw.

Overall, long-term smoking shortens life expectancy by 12-15 years.

"This well conducted study confirms what epidemiologists have suspected but few among the public have," commented University of Oxford professor Paul Aveyard, who was not involved in the research.

"The implication is obvious -- anyone who smokes should stop."

At the same time, he added, it would be wrong to conclude that cutting down is useless.

"There is more reason to believe that lower cigarette consumption will reduce the risk of chronic lung disease and lung cancer, the other two big causes of early death from smoking," he said via Britain's Science Media Centre.

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Agencies
January 12,2020

Washington D.C., Jan 12: Disruption in one night's sleep can lead to getting Alzheimer's disease, a recent study has stated.

The interruption in the sound sleep for a single night aggravates the level of tau protein in any young male's body, thus gives rise to the chances of developing the disease.

According to CNN, the report was published on Wednesday in neurology, the medical journal of the American Academy of Neurology.

"Our study focuses on the fact that even in young, healthy individuals, missing one night of sleep increases the level of tau in blood suggesting that over time, such sleep deprivation could possibly have detrimental effects," says study author Dr Jonathan Cedernaes, a neurologist at Uppsala University in Sweden.

As defined by the Alzheimer's Association, tau is the name of a protein that helps in stabilizing the internal structure of the brain's nerve cells. An abnormal build-up of tau protein in the body can end up in causing interior cells to fall apart and eventually developing Alzheimer's.

"When you get more of that deep sleep and you get the REM sleep in the normal amounts, that improves clearance of abnormal proteins which we think is good," said Mayo Clinic neurologist Dr Donn Dexter, not the study author but a fellow of the American Academy of Neurology.

Earlier studies have also shown that getting deprived of sleep can allow higher tau development and accumulation. Thus that poor sleep can hasten the development of cognitive issues.

Researchers caution that the study is small and inconclusive, and acknowledged they were not able to determine what the increased levels might mean.

"This study raises more questions than answers," agreed Dexter on a concluding note, sharing, "What this is telling us is that we have to dig more deeply. Despite something we do for a third of our lives, we know so little about sleep and we're learning every day, particularly when it comes to sleep and dementia."

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Agencies
February 6,2020

Researchers have found the rates of lung cancer are higher in young women than men.

The study, published in the journal Pediatrics, examined lung cancer rates in young adults in 40 countries across five continents and uncovered a trend of higher lung cancer rates in women compared with men in recent years.

The emerging trend was widespread, affecting countries across varied geographic locations and income levels.

The changes appeared to be driven by a rising rate of adenocarcinoma lung cancer among women, said the study researchers from University of Calgary in Canada.

Lung cancer rates have been higher among men than women because men started smoking in large numbers earlier and smoked at higher rates; however, recent studies have reported converging lung cancer incidence rates between sexes.

Among men, age specific lung cancer incidence rates generally decreased in all countries, while in women the rates varied across countries with the trends in most countries stable or declining, albeit at a slower pace compared to those in men.

For the findings, lung and bronchial cancer cases between 30-64 age group from 1993-2012 were extracted from cancer incidence in five continents.

The study found the higher emerging rates of lung cancer in young women compared to young men.

According to the researchers, future studies are needed to identify reasons for the elevated incidence of lung cancer among young women.

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Agencies
May 30,2020

Drinking coffee may help reduce the risk of certain digestive disorders, including gallstone disease and pancreatitis, a new study has suggested.

The study from the Institute for Scientific Information on Coffee (ISIC) also highlighted other beneficial effects that coffee consumption may have on the process of digestion, including supporting gut microflora and promoting gut motility.

"Data indicates benefits against common digestive complaints such as constipation, as well as a potential reduction in the risk of more serious conditions like chronic liver diseases," said study author Carlo La Vecchia from the University of Milan in Italy.

Gallstone disease is a common digestive disorder, caused by the accumulation of gallstones in the gallbladder or bile duct, which affects approximately 10-15 per cent of the adult population.

While the mechanism by which coffee may protect against gallstone disease is not yet known, it has been observed that the risk for the condition declines with increasing daily consumption of coffee, the researchers said.

Caffeine is thought to play a role in these associations, as the same effect is not observed with decaffeinated coffee.

A common question among consumers and focus area for research is whether coffee is associated with heartburn or gastro-oesophageal reflux disease (GORD).

While a small number of studies have suggested an association between coffee drinking and GORD, the majority of studies reviewed suggest that coffee is not a major trigger of these conditions.

The report also reviewed a growing area of health and nutrition research, namely: the effect of coffee on the gut microflora (microorganism populations).

Recent studies suggest that populations of the beneficial gut bacteria Bifidobacterium spp, increase after drinking coffee.

The findings showed the dietary fibre and polyphenols found in coffee, support the healthy growth of microflora populations.

Additional research findings highlighted that coffee consumption is thought to stimulate digestion by encouraging the release of gastric acid, bile and pancreatic secretions.

Coffee is one of the most widely researched components of the diet, and its effect on digestion remains a growing area of research, the researchers noted.

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