Heart risks linked to ‘food deserts’ caused by costs, not lack of access

September 24, 2017

Living in an area with little access to fresh and nutritious foods has been linked to high heart disease risk, but a new study suggests that it’s the inability to afford a healthy diet, rather than access, that’s to blame.

Researchers studied Atlanta residents and found that people living in “food deserts,” where there are few places to buy fresh produce and other healthy foods, had more heart risk factors like hardened arteries and inflammation than people with easy access to healthy foods.

But within food-desert neighborhoods, people with high personal income had fewer heart risk factors than those with low incomes, suggesting it’s money, not access, that prevents some people from having a healthy diet that would lower their heart risk, the study team concludes in Circulation: Cardiovascular Quality and Outcomes.

“Food deserts are defined as areas that have below average income together with poor access to healthy foods, ie. lack of grocery stores (within 1 mile in urban and 10 miles in rural communities),” lead author Dr. Arshed Quyyumi told Reuters Health in an email.

“We found that area income, and even more importantly, personal income was associated with higher cardiovascular risk, and that access to food was not that important a risk,” said Quyyumi, a cardiologist at Emory University School of Medicine in Atlanta.

Researchers have known that neighborhood factors are important social determinants of disease outcomes, he added.

For the study, Quyyumi and his colleagues examined data on more than 1,400 adults, averaging about 50 years old, and living in the Atlanta metropolitan area. Just under 40 percent were men and about 37 percent were African American.

The researchers collected personal and economic information and performed tests to detect signs of inflammation, elevated blood sugar and blood pressure, as well as arterial stiffness.

About 13 percent of participants lived in areas considered food deserts. These people also had higher rates of smoking, were more likely to have high blood pressure and hardened arteries and to be overweight or obese, compared to those not living in food deserts.

When the study team took average neighborhood income and individual incomes into consideration, they found that people living in food deserts in low-income areas had about the same risk of heart disease as their peers living in low-income areas with good food access.

Meanwhile, high-income individuals in low-income neighborhoods had fewer cardiovascular risk factors compared to their lower-income neighbors, and that was true even when they lived in food deserts.

“People not having access to healthy food choices is a possible cause for poor health. However, our study shows the greater impact of lower socio-economic status as a stronger risk factor,” Quyyumi said.

The study team was partly surprised to find so little impact from food access, he said, but speculated

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Agencies
May 2,2020

Clinician-scientists have found that Irish patients admitted to hospital with severe coronavirus (COVID-19) infection are experiencing abnormal blood clotting that contributes to death in some patients.

The research team from the Royal College of Surgeons in Ireland found that abnormal blood clotting occurs in Irish patients with severe COVID-19 infection, causing micro-clots within the lungs.

According to the study, they also found that Irish patients with higher levels of blood clotting activity had a significantly worse prognosis and were more likely to require ICU admission.

"Our novel findings demonstrate that COVID-19 is associated with a unique type of blood clotting disorder that is primarily focussed within the lungs and which undoubtedly contributes to the high levels of mortality being seen in patients with COVID-19," said Professor James O'Donnell from St James's Hospital in Ireland.

In addition to pneumonia affecting the small air sacs within the lungs, the research team has also hundreds of small blood clots throughout the lungs.

This scenario is not seen with other types of lung infection and explains why blood oxygen levels fall dramatically in severe COVID-19 infection, the study, published in the British Journal of Haematology said.

"Understanding how these micro-clots are being formed within the lung is critical so that we can develop more effective treatments for our patients, particularly those in high-risk groups," O'Donnell said.

"Further studies will be required to investigate whether different blood-thinning treatments may have a role in selected high-risk patients in order to reduce the risk of clot formation," Professor O'Donnell added.

According to the study, emerging evidence also shows that the abnormal blood-clotting problem in COVID-19 results in a significantly increased risk of heart attacks and strokes.

As of Friday morning, the cases increased to 20,612 cases in Ireland, with 1,232 deaths so far, according to the Johns Hopkins University.

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News Network
July 10,2020

Toronto, Jul 10: Pasteurising breast milk at 62.5 degrees Celsius for 30 minutes inactivates the SARS-CoV-2 virus that causes Covid-19, making it safe for consumption by babies, a study claims.

According to the research published in the Canadian Medical Association Journal, current advice for women with Covid-19 is to continue to breastfeed their own infants.

In Canada, it is standard care to provide pasteurised breast milk to very-low-birth-weight babies in hospital until their own mother's milk supply is adequate, the researchers said.

"In the event that a woman who is Covid-19-positive donates human milk that contains SARS-CoV-2, whether by transmission through the mammary gland or by contamination through respiratory droplets, skin, breast pumps and milk containers, this method of pasteurisation renders milk safe for consumption," said Sharon Unger, a professor at the University of Toronto in Canada.

The Holder method, a technique used to pasteurise milk in all Canadian milk banks at 62.5 degrees Celsius for 30 minutes, is effective at neutralising viruses such as HIV, hepatitis and others that are known to be transmitted through human milk, the researchers said.

In the latest study, the researchers spiked human breast milk with a viral load of SARS-CoV-2 and tested samples that either sat at room temperature for 30 minutes or were warmed to 62.5 degrees Celsius for 30 minutes.

They then measured for active virus, finding that the virus in the pasteurised milk was inactivated after heating.

More than 650 human breast milk banks around the world use the Holder method to ensure a safe supply of milk for vulnerable infants, the researchers said.

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Agencies
May 26,2020

Tedros Adhanom Ghebreyesus, the World Health Organisation's (WHO) Director-General, said that a clinical trial of hydroxychloroquine (HCQ) on COVID-19 patients has come to "a temporary pause", while the safety data of the the anti-malaria drug was being reviewed.

According to the WHO chief, The Lancet medical journal on May 22 had published an observational study on HCQ and chloroquine and its effects on COVID-19 patients that have been hospitalized, reports Xinhua news agency.

The authors of the study reported that among patients receiving the drug, when used alone or with a macrolide, they estimated a higher mortality rate.

"The Executive Group of the Solidarity Trial, representing 10 of the participating countries, met on Saturday (May 23) and has agreed to review a comprehensive analysis and critical appraisal of all evidence available globally," Tedros said in a virtual press conference on Monday.

The review will consider data collected so far in the Solidarity Trial and in particular robust randomized available data, to adequately evaluate the potential benefits and harms from this drug, he said.

"The Executive Group has implemented a temporary pause of the HCQ arm within the Solidarity Trial while the safety data is reviewed by the Data Safety Monitoring Board. The other arms of the trial are continuing," Tedros added.

WHO initiated the Solidarity Trial, a plan to evaluate the safety and efficacy of four drugs and drug combinations against COVID-19 more than two months ago, which include HCQ.

According to the WHO, over 400 hospitals in 35 countries are actively recruiting patients and nearly 3,500 patients have been enrolled from 17 countries under the Solidarity Trial.

Tedros added that the safety concern over the drug related only to the use of HCQ and chloroquine in COVID-19, and "these drugs are accepted as generally safe for use in patients with autoimmune diseases or malaria".

"WHO will provide further updates as we know more," he added.

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