Help baby Pranavi battle blood cancer

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangaluru, May 13: Coastal district of Dakshina Kannada today reported a fresh covid-19 positive case. According to sources, this case also linked to Manglauru’s First Neuro Hospital, which has emerged as the corona hub of coastal Karnataka.

Health and Family Welfare department in its today’s bulletin revealed that a 38-year-old woman from Darandabagilu near Someshwara in Mangaluru taluk of Dakshina Kannada was tested coronavirus positive.

It is said that the woman was in touch with P-507, an octogenarian, who was being treated for neurological issues at First Neuro Hospital.

With this the total number of coronavirus positive cases reported in Dakshina Kannada rose to 34. Among them only 26 are residents of Dakshina Kannada. Four are from Kasaragod, three from Udupi and one from Bhatkal.

Among 34, currently there only 17 active cases. The condition of two among them is said to be critical.

Bengaluru, Jul 24: To condemn violence on healthcare workers and to voice issues concerning medical fraternity, Karnataka Association Of Resident Doctors (KARD) has called for a nationwide symbolic protest from July 24.

"In order to condemn violence on healthcare workers and to voice all our issues, we have called nationwide symbolic protest from July 24. We will protest symbolically by wearing black bands, across the state and have sought support from residents pan-India," KARD said in a statement.

"We, the resident doctors of Karnataka have been undergoing various difficulties while executing our duties during the COVID-19 pandemic," it added.

"Arrest and legal action against culprits involved in K.C General hospital incident. Arrest and legal action against culprits involved in Belgaum incident. Condemnation of atrocities on doctors in Bidar and action against the official. Ensuring safety protocols at all hospitals and COVID care centres with adequate security and police personnel," KARD demanded.

"No hierarchy in a pandemic"- common work pattern for all doctors irrespective of hierarchy/cadre. Immediate release of funds for a stipend for an already sanctioned hike. COVID duty and night duty allowances. Ensuring an adequate supply of N-95 masks, face shields, surgical gowns in all non-COVID working areas. An adequate supply of good quality PPEs for all COVID working areas," KARD demanded.

Earlier, the nurses of Karnataka Institute of Medical Sciences (KIMS) in Hubli called off the protest after receiving assurance from Nitish Patil, the Dharwad district Deputy Commissioner (DC).

The protest was staged on Wednesday afternoon in front of KIMS by nurses who alleged that the administration had not provided adequate Personal Protective Equipment (PPE) kits, masks and sanitary facilities amid the COVID-19 pandemic situation.