May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
A very good reply by CM and excellent comparison of Karnataka with the jungle raj UP.
We need no lessons here, especially from sectarian leaders of the North.
Well said , BY our CM, Hats off to you! Dear Siddaramaih Humble peace loving CM of KARNATAKA
sir, reasonably all were hindus. INDIA invaders made attacks and several sects were forceful followed the other category I feel!
ALL ARE HINDUS . BUT SOMETIMES SOMEBODIES FEELTHAT TEY ARE!
2 c.m. of YOGI MAY HAD DONE REMARKS AS TUTTURI BECAUSE THEY ARE LEAST AQUENTED WITH KARNATAKA.
THERE WERE KINGS AND QUEENS RULING INDIA ONE OF THOSE MAY BE TIPPU AGAINST BRITISH!! ONLY MERITS OF TIPPU BE COUNTED FOR CELEBRATIONS AFTER INDEPENDENCE> THERE MAY NOT BE ANY SPECIALTY BUT WILL!
* HANUMAN is treated as WIND GOD and there is no need to compare with TIPPU(DEEP) i FEEL!
** YOGY WAS OF VISIT FOR PRIVATE CAUSE AND THERE WAS NO NEDOF CRITICIZING KARNATAKA ADMINISTRATION. WHICH KNOWN LITTLE FACT OF IT TO HIM!!. NOT GOOD TO PEEP IN THE ADMINISTRATION OF OTHER STATE IS FEDARAL STATE POLICY!!
Karnataka state comes under fit state of administration on federal ground - in all respects, the speaker must study before making any comments about Karnataka.Hanuman differs from any kings of India now and before also
Double agent Hindus like you do anything for power & money
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