Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
This passage has always been quoted out of context and never post other verses 9:1-14, If they did, people would find out that it says the opposite of what they claim. Read from 9:1 – 9:14,
Islam never says to kill non-believers and this wording is related to pagans at the time of renovation. Quran is not an ordinary book. To understand the quran better you need to study Hadith and history. Dear brother Rudra I really appreciate your quote and I advise you to study more and more about islam to find truth. May Almighty Allah Guide you and your family in a right way. May Allah bless you if he wishes. Insha halla
Dear Asokan, dont trust on sanghis who are trying to brain wash you. Whatever you have stated is wrong. Your daughter has no passport to go out of india. Secondly your son-in-law is not a terrorist but those sanghis who are brain washing are the real terrorists who killed Bapuji.
All claims, no proof.
Kill unbelievers where you find them. koran 9:5
Do you dare to deny it? Do you follow it ? pseudo muslim.
As per Quran, All muslims are not terrorists, there is no doubt in it.
I agree with you whatever legal points of view expressed. Hadiya is matured, educated lady and free to convert, believe and marry the boy of her choice.
There is another face to this, which also to be a face of parents! irrespective of Ashokan's Sangh parivar leanings, keep in mind that he is father of Hadiya.They born & bought up her for 24 years and all of sudden they lost her! How their agony, misery and sufferings will be? Just keep us in his place and think, don’t we require little introspection?
Mr.Ashokan Miscerabley failed to prove his claim as said! now even the supereme court allowed Hadiya to meet Mr.Shafin Jahan! the above statement is out of his frustration he maight have said. Now a days it is very easy to paint some one as terrorist , and some as nationalist! media and some Govt. agency under RSS control anything may happen in future as they decide who is nationalist and who is anti national!
Pray for Mr.Ashokan, Please read Islamic history before you comment.
Every one misunderstood that accepting islam is just taking membership. Islam is way of Life proved scientifically and logically. It is just way of Life. any one can learn Islam and practise it. It is open and no body will force to accept islam. It is choice to practise Law defined by Our creator. No body wil be a True Muslim unless he practice the way of life defined by creator. increasing membership in islam no use. Every one should understand their creator and obey him. It is very simple and beautiful. If any one understand the principles of Islam. automatically he will attract. and identify his creator. Only our creator can read our mind and understand true believer. by name we cannot say he is true beleiver.
"If thousands of crminals escape also no innocent should be punished"
"one should not eat full if neighbour is starving"
what a beautiful teaching. We pray Al mighty Allah shows right path for all human being.
Now he need Treatment from Mental Hospital.
How dare Asokan to call a man terrorist without a proof ?
He has the rights to object to the marriage but, can't call a man terrorist.
Drag him to court of law for defamation.
LOL
mr. jahan, file defamation case against this ignorant human...
In sha allah on judgment day hadiya's father will realize that her daughter had made a right decission by entering to the fold of islam and saved her life from hell fire. But sad part is her father is not realizing this now. I pray with almighty that to give hidayah to hadiya's father.
If ALLAH wills, one day you will come to realise that my daughter hadiya has taken a good descision, from dark to light. and i hope that hadiyas entire family will be enter to islam. May ALLAH guide you to understand islam. Aameen.
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