Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
Dear Viren there is nothing hell in your religion, thats the reason they are coming towards islam
very funny.
Dear All,
Please note few of these points about Islam.
Wish you all the best. May God bless you with happiness and good health always and you lead a happy life forever. Our prayers are with you. But try to keep away from unnecessary things and lead a simple life.
Bro.. its other way round. Hindu girls are falling love with handsome guys and beautiful religion
This is called true Islam. When 27 Karsevaks like Balbir Singh can embrace Islam , you just imagine the power of Islam.
Mix equal quantity of love and jihad in a cup and drink it...
and dont forget to buy burnol to cool off your bloody b***
Read the quran with translated original (not chaddis version). U Will end up in Reverting Islam.. In Sha Allah.
In the Quran the chilling & fearful explanation of Hell fire & HELL is there to those who reject ONE CREATOR and associate partners with him and worship all those demi-gods.
LOVE of His True last messenger & ONE CREATOR is the only way to escape from the HELL fire and attain HEAVEN.
JIHAD – constant struggle with oneself to be obedient to God, struggle (Jihad) against oppression of all kinds unleashed by enemies of humanity.
It is human nature to search for truth and aspire purity rejecting all manmade, false, ungodly beliefs & customs. No force on the earth can stop this and that is the reason thousands are attracted on daily basis to the Religion of Peace & Truth - ISLAM.
How long will YOU ignorants blame love jehad.. We request you to OPEN the QURAN (the quranproject) online and check what is written about love jehad... Unless YOU learn about quran .... YOU are following the RSS commandments and singing the same tone (it's love jehad) since years... When U guys open up your God given intellect.. Dont be SLAVES of RSS ... Use your intellect to know WHY PEOPLE are REVERTING to ISLAM... instead of blaming and licking the politicians and the haters of Islam.
This all happens because you bloody morons donot understand what is love and care all about.
Go drink sleep on streets, make your wife & childrens (some people dont have that too) wait home, come home next morning once again in Bar... Your life begins and Ends in BAR & Restaurent.
Dear Brother Study about Islam than you come to know what the hell is there in Islam (Alhamdulillah).
Congrats Shoaib
There are many cases like this. They all get converted into islam. There is racket to do conversion. Should stop this.. Stop Love Jihad
Stockholm syndrome by love jihad.. She may not feel trapped now. Later she feels that
Media highlighting only if anybody comes to Islam.. Pleasing minority
We wont care, if she got converted into christianity or other religion. Media giving unwanted prominants to some rubbish news. They are making controversy
Is that an important news
This is called love jihad. These muslim men make friendship with beautiful Hindu girls, make them fall in love with them. After wedding blackmail them to become Muslims. Need to put an end to this ugly practice at the earliest. What the hell is there in that religion.
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