India enters age of 3D printed body parts

February 26, 2017

Gurgaon, Feb 26: 3D printed body parts have become a reality in India, a game changer which promises to alter the medical landscape in India.3d

The courage of a school teacher has ushered in almost unnoticed a quiet medical revolution in India with links that spread from Bareilly to Gurgaon.

A doctor from Metro Hospital, Noida said, "3D printing is indeed an upcoming innovation offering personalised medicine."

Efforts are also being made to master the same technique on living tissue to replace full organs but that is still some distance away. Imagine printing a copy of your own kidney to replace a damaged one!

Earlier this month, a team of young doctors from Medanta: The Medicity in Gurgaon on the outskirts of the capital successfully performed a surgery on the failing spine of a woman and inserted for the first time a 3D printed titanium implant giving the woman a completely new lease of life.

Almost miraculously four days after the surgery, the woman was walking. Had traditional surgical techniques been adopted, according to the doctors she would have walked after months.

Dr Naresh Trehan, founder of Medanta, said, "3D printing technology has opened up whole new vista to re-create body parts to save lives."

After a school teacher suffered a debilitating collapse of her neck vertebra due to TB, doctors from Medanta claimed to have used Indias first 3D printed titanium implant to bring the patient back from near collapse to near normal life.

Last month, walking and talking were a Herculean task for the 32-year-old patient who is also a dancer and singer, her neck was collapsing, as the TB bug had slowly consumed the second and third vertebra in her neck.

Once the spinal cord started getting compressed, the woman started losing sensation on all her limbs, making life very difficult.

After a first-of-its-kind surgery in India, she can now hope to lead a near normal life. Having undergone a 10-hour surgery of February 3, the patient who does want to be identified, said, "Im better now, but towards the end I had a lot of problem. I was not able to walk, I could not sleep at night because of the pain nor could I do anything. Now I am feeling much better."

Faced with this complex medical problem, a team of 10 health specialists decided to deploy for the first time a custom made ultra-modern 3D printed titanium implant to replace the two infected vertebra in her neck.

The other option would have been to use a piece of bone from the patients own leg but that would have, according to the medical team, kept her in the bed for more than 6 months after the surgery.

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Agencies
February 27,2020

Washington D.C, Feb 27: New research shows that adults who have low fruit and vegetable intake are more likely to be diagnosed with an anxiety disorder.

"For those who consumed less than 3 sources of fruits and vegetables daily, there was at least at 24% higher odds of anxiety disorder diagnosis," says the lead author of the Canadian Longitudinal Study, Karen Davison, who is a health science faculty member, nutrition informatics lab director at Kwantlen Polytechnic University, (KPU) and North American Primary Care Research Group Fellow.

"This may also partly explain the findings associated with body composition measures. As levels of total body fat increased beyond 36%, the likelihood of anxiety disorder was increased by more than 70%," states co-author Jose Mora-Almanza, a Mitacs Globalink intern who worked with the study at KPU.

"Increased body fat may be linked to greater inflammation. Emerging research suggests that some anxiety disorders can be linked to inflammation," says Davison.

In addition to diet and body composition measures, the prevalence of anxiety disorders also differed by gender, marital status, income, immigrant status and several health issues.

An important limitation of the study was that the assessment of anxiety disorders was mostly based upon self-reporting of a medical diagnosis.

"It is estimated that 10% of the global population will suffer from anxiety disorders which are a leading cause of disability," says Karen Davison

"Our findings suggest that comprehensive approaches that target health behaviours, including diet, as well as social factors, such as economic status, may help to minimize the burden of anxiety disorders among middle-aged and older adults, including immigrants," she concluded.

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July 8,2020

Probiotics that broaden the mix of helpful bacteria in the gut may help to ease depression, say researchers.

Foods that broaden the profile of helpful bacteria in the gut are collectively known as probiotics. These "good bacteria" can be taken as supplements, or found naturally in yoghurts or fermented foods.

For the findings, the research team from the University of Brighton in the UK searched for relevant studies published in English between 2003 and 2019, which looked at the potential therapeutic contribution of pre-and probiotics in adults with depression and/or anxiety disorders.

Out of an initial haul of 71 studies, just seven met all the criteria for inclusion. All 7 investigated at least one probiotic strain; four looked at the effect of combinations of multiple strains.In all, 12 probiotic strains featured in the selected studies, primarily Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium bifidium.

One study looked at combined pre-probiotic treatment, while one looked at prebiotic therapy by itself. The studies varied considerably in their design, methods used, and clinical considerations, but all of them concluded that probiotic supplements either alone or in combination with prebiotics may be linked to measurable reductions in depression.

And every study showed a significant fall or improvement in anxiety symptoms and clinically relevant changes in biochemical measures of anxiety or depression with probiotic or combined pre-probiotic use.

Of the 12 different probiotics investigated, 11 were potentially useful, the findings showed.'Probiotics may help reduce the production of inflammatory chemicals, such as cytokines, as is the case in inflammatory bowel disease, the researchers suggested.

"They may help direct the action of tryptophan, a chemical thought to be important in the gut-brain axis in psychiatric disorders," they added.

In this way, with a better understanding of the mechanisms, probiotics may prove to be a useful tool across a wide range of conditions," the authors wrote.

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May 30,2020

Drinking coffee may help reduce the risk of certain digestive disorders, including gallstone disease and pancreatitis, a new study has suggested.

The study from the Institute for Scientific Information on Coffee (ISIC) also highlighted other beneficial effects that coffee consumption may have on the process of digestion, including supporting gut microflora and promoting gut motility.

"Data indicates benefits against common digestive complaints such as constipation, as well as a potential reduction in the risk of more serious conditions like chronic liver diseases," said study author Carlo La Vecchia from the University of Milan in Italy.

Gallstone disease is a common digestive disorder, caused by the accumulation of gallstones in the gallbladder or bile duct, which affects approximately 10-15 per cent of the adult population.

While the mechanism by which coffee may protect against gallstone disease is not yet known, it has been observed that the risk for the condition declines with increasing daily consumption of coffee, the researchers said.

Caffeine is thought to play a role in these associations, as the same effect is not observed with decaffeinated coffee.

A common question among consumers and focus area for research is whether coffee is associated with heartburn or gastro-oesophageal reflux disease (GORD).

While a small number of studies have suggested an association between coffee drinking and GORD, the majority of studies reviewed suggest that coffee is not a major trigger of these conditions.

The report also reviewed a growing area of health and nutrition research, namely: the effect of coffee on the gut microflora (microorganism populations).

Recent studies suggest that populations of the beneficial gut bacteria Bifidobacterium spp, increase after drinking coffee.

The findings showed the dietary fibre and polyphenols found in coffee, support the healthy growth of microflora populations.

Additional research findings highlighted that coffee consumption is thought to stimulate digestion by encouraging the release of gastric acid, bile and pancreatic secretions.

Coffee is one of the most widely researched components of the diet, and its effect on digestion remains a growing area of research, the researchers noted.

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