Indian rural women late in seeking breast cancer care: study

Agencies
March 23, 2018

London, Mar 23: Women in rural India delay seeking treatment for breast cancer mostly due to high costs of care, according to a study which found that many of them have not even heard of the deadly disease.

The study by Nitin Gangane, a doctoral student at Umea University in Sweden, also found that most Indian women do not know how to do breast self-exams.

"Early detection may be crucial for successful breast cancer treatment. Therefore, it is important to influence women's awareness of the symptoms and their attitudes towards treatment," said Gangane.

"Illiteracy, ignorance, poverty and superstition regretfully lead to many women delaying their contact with the health care system too long," he said.

Gangane performed two studies of women in the mainly rural-dominated district of Wardha in Maharashtra.

The first study consisted of a sample of 1,000 women interviewed about socioeconomic factors, knowledge of breast cancer and attitudes to breast self-examination.

The second study was a patient study in the same district where 212 women with breast cancer were included.

It turned out that hardly any women in the studies self-examined their breasts.

As many as 90 percent of women in rural areas were unaware of the possibility of self-examination of their own breasts, the study found.

Every third woman had not heard of breast cancer at all. On the other hand, most of the women showed a great deal of interest in learning more, it found.

A delay for more than three months of seeking care was observed in almost half of the women, said Gangane.

The delay in diagnosis and treatment for more than twelve weeks was seen for 23 percent of patients.

The most common reason why women had not sought care earlier was that they had not felt any pain in the breast lump.

Incorrect initial diagnosis or late referral to examination was the most common cause of diagnostic delay, according to the study.

Delayed treatment was mostly due to the high costs associated with treatment, it found.

However, system delays for breast cancer patients associated with healthcare in the Indian countryside were not much higher than those reported from countries with good access to health care.

"It is urgent to have a national breast cancer program in India, while at the local level, we need to raise awareness among women about breast cancer," said Gangane.

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Agencies
March 27,2020

New Delhi, Mar 27: The Centre has restricted sale and distribution of "hydroxychloroquine" declaring it as an essential drug to treat the COVID-19 patients and meet the requirements of emergency arising due to the pandemic.

The Ministry of Health and Family Welfare on Thursday made the announcement making it clear that the order "shall come into force on the date of its publication in the official Gazette".

In the order, the government declared that the Central government is "satisfied that the drug hydroxychloroquine is essential to meet the requirements of emergency arising due to pandemic COVID-19 and in the public interest, it is necessary and expedient to regulate and restrict the sale and distribution of the drug 'hydroxychloroquine' and preparation based thereon for preventing their misuse".

"Now, therefore, in exercise of the powers conferred by Section 26B of the Drugs and Cosmetics Act, 1940 (23 of 1940), the Central government hereby directs that sale by retail of any preparation containing the drug Hydroxychloroquine shall be in accordance with the conditions for sale of drugs specified in Schedule H1 to the Drugs and Cosmetics Rules, 1945."

The order came at a time when the novel coronavirus claimed 16 lives and infected over 600 people across India.

The announcement regarding ban of sale and distribution of the drug was made by the government earlier but it issued an official Gazette notification on Thursday signalling that hydroxychloroquine -- an anti-Malaria drug -- will work as a medicine for treating coronavirus infected patients as well.

Recently, the national task force for COVID-19 constituted by Indian Council for Medical Research (ICMR) has recommended hydroxy-chloroquine as a preventive medication.

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Agencies
July 8,2020

Probiotics that broaden the mix of helpful bacteria in the gut may help to ease depression, say researchers.

Foods that broaden the profile of helpful bacteria in the gut are collectively known as probiotics. These "good bacteria" can be taken as supplements, or found naturally in yoghurts or fermented foods.

For the findings, the research team from the University of Brighton in the UK searched for relevant studies published in English between 2003 and 2019, which looked at the potential therapeutic contribution of pre-and probiotics in adults with depression and/or anxiety disorders.

Out of an initial haul of 71 studies, just seven met all the criteria for inclusion. All 7 investigated at least one probiotic strain; four looked at the effect of combinations of multiple strains.In all, 12 probiotic strains featured in the selected studies, primarily Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium bifidium.

One study looked at combined pre-probiotic treatment, while one looked at prebiotic therapy by itself. The studies varied considerably in their design, methods used, and clinical considerations, but all of them concluded that probiotic supplements either alone or in combination with prebiotics may be linked to measurable reductions in depression.

And every study showed a significant fall or improvement in anxiety symptoms and clinically relevant changes in biochemical measures of anxiety or depression with probiotic or combined pre-probiotic use.

Of the 12 different probiotics investigated, 11 were potentially useful, the findings showed.'Probiotics may help reduce the production of inflammatory chemicals, such as cytokines, as is the case in inflammatory bowel disease, the researchers suggested.

"They may help direct the action of tryptophan, a chemical thought to be important in the gut-brain axis in psychiatric disorders," they added.

In this way, with a better understanding of the mechanisms, probiotics may prove to be a useful tool across a wide range of conditions," the authors wrote.

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