Indians lose over four years of their lives to air pollution, says study

Agencies
November 26, 2018

Nov 26: According to the new Air Quality Life Index (AQLI), developed by researchers at University of Chicago in the US, particulate air pollution cuts global average life expectancy by 1.8 years per person.

People in India would live an average 4.3 years longer if the country met the global guidelines for particulate pollution, according to a study which found that effect of pollution on life expectancy is worse than HIV/AIDS, cigarette smoking, and even terrorism. According to the new Air Quality Life Index (AQLI), developed by researchers at University of Chicago in the US, particulate air pollution cuts global average life expectancy by 1.8 years per person.

The AQLI establishes particulate pollution as the single greatest threat to human health globally, with its effect on life expectancy exceeding that of devastating communicable diseases such as tuberculosis and HIV/AIDS, behavioural killers like cigarette smoking, and even war.

Critically, the AQLI reports these results in tangible terms that are relatable for most people.

“Around the world today, people are breathing air that represents a serious risk to their health. But the way this risk is communicated is very often opaque and confusing, translating air pollution concentrations into colors, like red, brown, orange and green,” said Michael Greenstone, a professor at Energy Policy Institute at the University of Chicago (EPIC).

“My colleagues and I developed the AQLI, where the ‘L’ stands for ‘life,’ to address these shortcomings. It takes particulate air pollution concentrations and converts them into perhaps the most important metric that exists: life expectancy,” he said.

The AQLI is based on a pair of studies that quantify the causal relationship between long-term human exposure to particulate pollution and life expectancy.

Seventy-five percent of the global population, or 5.5 billion people, live in areas where particulate pollution exceeds the WHO guideline.

The AQLI reveals that India and China, which make up 36 per cent of the world’s population, account for 73 per cent of all years of life lost due to particulate pollution.

On average, people in India would live 4.3 years longer if the country met the WHO guideline — expanding the average life expectancy at birth there from 69 to 73 years.

In the US, about a third of the population lives in areas not in compliance with the WHO guideline. Those living in the country’s most polluted counties could expect to live up to one year longer if pollution met the WHO guideline.

Globally, the AQLI reveals that particulate pollution reduces average life expectancy by 1.8 years, making it the greatest global threat to human health.

By comparison, first-hand cigarette smoke leads to a reduction in global average life expectancy of about 1.6 years. Other risks to human health have even smaller effects: Alcohol and drugs reduce life expectancy by 11 months; unsafe water and sanitation take off 7 months; and HIV/AIDS, 4 months.

Conflict and terrorism take off 22 days. So, the impact of particulate pollution on life expectancy is comparable to that of smoking, twice that of alcohol and drug use, three times that of unsafe water, five times that of HIV/AIDS, and more than 25 times that of conflict and terrorism.

“While people can stop smoking and take steps to protect themselves from diseases, there is little they can individually do to protect themselves from the air they breathe,” Greenstone said.

“The AQLI tells citizens and policymakers how particulate pollution is affecting them and their communities and reveals the benefits of policies to reduce particulate pollution,” he said.

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Agencies
July 7,2020

The World Health Organization (WHO) is reviewing a report that suggested its advice on the novel coronavirus needs updating after some scientists told the New York Times there was evidence the virus could be spread by tiny particles in the air.

The WHO says the Covid-19 disease spreads primarily through small droplets, which are expelled from the nose and mouth when an infected person breaths them out in coughs, sneezes, speech or laughter and quickly sink to the ground.

In an open letter to the Geneva-based agency, 239 scientists in 32 countries outlined the evidence they say shows that smaller exhaled particles can infect people who inhale them, the newspaper said on Saturday.

Because those smaller particles can linger in the air longer, the scientists - who plan to publish their findings in a scientific journal this week - are urging WHO to update its guidance, the Times said.

"We are aware of the article and are reviewing its contents with our technical experts," WHO spokesman Tarik Jasarevic said in an email reply on Monday to a Reuters request for comment.

The extent to which the coronavirus can be spread by the so-called airborne or aerosol route - as opposed to by larger droplets in coughs and sneezes - remains disputed.

Any change in the WHO's assessment of the risk of transmission could affect its current advice on keeping one-metre physical distancing. Governments, which also rely on the agency for guidance policy, may also have to adjust public health measures aimed at curbing the spread of the virus.

"Especially in the last couple of months, we have been stating several times that we consider airborne transmission as possible but certainly not supported by solid or even clear evidence," Benedetta Allegranzi, the WHO's technical lead for infection prevention and control, was quoted as saying in the New York Times.

WHO guidance to health workers, dated June 29, says that SARS-CoV-2, the virus that causes Covid-19, is primarily transmitted between people through respiratory droplets and on surfaces.

But airborne transmission via smaller particles is possible in some circumstances, such as when performing intubation and aerosol-generating procedures, it says.

Medical workers performing such procedures should wear heavy-duty N95 respiratory masks and other protective equipment in an adequately ventilated room, the WHO says.

Officials at South Korea's Centers for Disease Control said on Monday they were continuing to discuss various issues about Covid-19, including the possible airborne transmission. They said more investigations and evidence were needed.

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Agencies
June 22,2020

A team of scientists has produced first open source all-atom models of full-length COVID-19 Spike protein that facilitates viral entry into host cells – a discovery that can facilitate a faster vaccine and antiviral drug development.

The group from Seoul National University in South Korea, University of Cambridge in the UK and Lehigh University in the US produced the first open-source all-atom models of a full-length S protein.

The researchers say this is of particular importance because the S protein plays a central role in viral entry into cells, making it a main target for vaccine and antiviral drug development.

"Our models are the first full-length SARS-CoV-2 spike (S) protein models that are available to other scientists," said Wonpil Im, a professor in Lehigh University.

"Our team spent days and nights to build these models very carefully from the known cryo-EM structure portions. Modeling was very challenging because there were many regions where simple modeling failed to provide high-quality models," he wrote in a paper published in The Journal of Physical Chemistry B.

Scientists can use the models to conduct innovative and novel simulation research for the prevention and treatment of Covid-19.

Though the coronavirus uses many different proteins to replicate and invade cells, the Spike protein is the major surface protein that it uses to bind to a receptor.

The total number of global COVID-19 cases was nearing 9 million, while the deaths have increased to over 467,000, according to the Johns Hopkins University.

With 2,279,306 cases and 119,967 deaths, the US continues with the world's highest number of COVID-19 infections and fatalities, according to the CSSE.

Brazil comes in the second place with 1,083,341 infections and 50,591 deaths.

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Agencies
April 14,2020

There is no evidence that the Bacille Calmette-Guerin (BCG) vaccine, which is primarily used against tuberculosis, protects people against infection with the novel coronavirus, the World Health Organization (WHO) said.

The WHO therefore didn't recommend BCG vaccination for the prevention of COVID-19 in the absence of evidence, according to its daily situation report on Monday, Xinhua news agency reported.

"There is experimental evidence from both animal and human studies that the BCG vaccine has non-specific effects on the immune system. These effects have not been well characterized and their clinical relevance remains unknown," WHO stated.

Two clinical trials addressing the question are underway, and WHO will evaluate the evidence when it is available, it noted.

BCG vaccination prevents severe forms of tuberculosis in children and diversion of local supplies may result in an increase of disease and deaths from the tuberculosis, it warned.

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