Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
Sick person....
Ivan D'souza should not go for it when Hindus don't like it.
Regarding religion, when all religious group agree there is only 1God, then that God will not permit to follow different religion.
So, why don't all people search for that true 1religion.
Don't follow any religion just because our ancestors followed it.
Dare to find and follow the truth.
Puranik keep ur diwali in ur temple it self dont bring it to our masjid. But u r welcome to our masjid as a human being bt not as a communal mongar
Any Master Blaster Puranik, which part of the world he is leaving, Like this Buffoons started Destroying the Hindustan, I do not understand, Temple, Church or Mosque all the place to worship for the Human being, in between there is religious wise, Cultural wise, Language wise all we Human made but God is same to all, it was happening before, why nowadays doing like this?????
What these Criminal Minded Puranik Climbing up some one, he Looted, he did alot of crimes and stored a lot for him and his belongs, all these Criminalism effects the Poor people, they will suffer, while coming to Poor there is no Bajjis, Raniss VHPS will not help. mind it all these Criminals only await to loot only.
In my Elder time I Entered all these places, no one said anything.
While I was is South Africa I see there are Two Foot path one For White One For Black, looks like, These Goondas looking to make like Hindustan, this is Destroying our God's own Country, That means all are sufferers okay Gentle Mans of Hindustan.
Purnikanna Do not bring your Personal Enmity to destroy our beautiful country.
Jai Hoo Hindustan
Jai Hoo Siddaramanna
Jai Hoo Moodiji.
Jai Bharath Matha.
Baratha mathe kayyalle, baratha dvaja illa....Desha drohigalu yaru?
Muslimaru yava baratha mathe ge jai helbeku? RSS!?
Jai hind, jai bharath. We are proud to be indian.
RSS, VHP, Bajrangdal should be BANNED. they are real trouble maker and anti national, those killed our Gandhiji.
Dear VHP Brothers
A true Muslims never entertain idol worship, Either it is DARGA OR DURGA. Dont dream of a Muslim converting to other religion. Rather we heartly welcomes you people to the true religion ISLAM, in sha Allah which you will realize one day. And the day is not far.
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