May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
saudi bopanna ka bap ka hai. And who are you to say whether it is a muslim country or not. boppa
Saudi tere bap ka hai Kya ? Saudi is NOT Muslim country,.
YES WE ARE WITH YOU
Exactly. this is the fake encounter and cops deserve the death penalty.
Katju rightly said. Murderers along with masterminds deserve it.The trend of fake encounters has to be stopped in future.
Yes, many Indians believe that it was custodial killing/fake encounter, and a good majority also agree with Katju. All these Indians, including Katju - A former supreme court judge, are Anti-Nationals.
Sanghi chappars calling a qualified Rtd. chief justice of supreme court \Desh Drohi\". I mean why do people even respond to such comments and trolls.
None the less, Katju is also against many Islamic values and practices. But in this case, he has raised his voice for justice."
#2 Bopanna, KSA
What are you doing in KSA? It is a muslim country and is it allowed to you to work there? How can you feed your family in the wealth which is earned in muslim country. You hate Ummah then in this case you are a hypocrite.
Remember this soon or later truth will prevail and that time you will be sad. In your view if Justice Katju is desh drohi then what about Praveen togadiya, Karnal purohith, sadhvi prajna, Swami asimanad and other all sangi terrorists??
You are right Mr.katju. Guys look @ video, and suspects prisoners were raising hands for surrender. But cops deliberately fired at them. And if you watch last night debate with bloody BJP spokesperson the way of answering was very shameful. Just they were struggling to answer the TV anchors questions.
Bopanna, if it had happened to you or any of your family member you would have felt the same thing.....no one has proved them guilty....they were under trial...police are not doing their job...instead encountering them by putting Simi tag....it is not good for a democratic country like India.....
How much does the Ummah pay you for such statements?
This guy is a Desh drohi
Death penalty for COPS in India !!!!!!!!!.....Forget it man
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