May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
This attack on Karnataka by BJP. Why did not they raid houses of BJP leaders who have become rich after BJP came to power. Reddy brothers are roaming freely and had lavesh wedding of their daughter. IT department are sleeping
Timing is good!!. Each one repeats same in cycle and then they may stop doing corruption. But Indian political population is a strange one and may start bribing each other! Congress also did all kind of tactics! Timing of investigation of corrupt DMK - daughter!
How can congress explain recovery of 10.5 crores cash from the minister's residence?Is it not embarrassing for congress leaders who called the raid witch - hunt?
What does BJP say about corruption of their own leaders. How many raids were given on the corrupt leaders of BJP. There are not hundred but thousand cases of corruption of BJP leaders. Recently in Chhatishgarh, one minister Brijmohan Aggarwal has encroached the government land. A few days ago Chief of Kerala BJP was caught for taking bribe of Rs 6 crores. After demonetization maximum black money was recovered from these BJP leaders. Before demonetization, dubious land deals were executed with their black money as they know fully that demonetization was to be declared by their party.. Black money was recovered from the BJP leader in Punjab as well from Madhya Pradesh leader. Who is funding Amit Shah who is roaming using chartered planes from one place t0 another place. What were the sources of funds during elections either for the Centre or for the states. Admitted Congress is corrupt but BJP is the most corrupt party in India.Wherefrom they got 15 crores to purchase MLAs.
All corrupt politicians are the feathers of the same bird. All are corrupt whether in the ruling party or in the opposition. Some of them are pro industrial and getting unaccountable money to be spent on their rival parties to let down. If any leader is corrupt and facing trial in the court, they either try to purchase the sitting judges or transfer them on the name of promotion. These tactics have been used by Modi Government in Gujarat to have clean chits in Godhara riots.The enquiry commission was appointed to enquire about who were behind the killings of innocent Sikhs, one Mishra was purchased by the Congress party and he was taken in Rajya Sabha.These commission heads are corrupt and working as per directions of the ruling party. How one can get justice. In India justice is denied to poor, downtrodden and minorities. These political parties have cleverly expert to change the facts into lies. They are expert to purchase and threaten others who are disagreed with them
How can there be black money? Demonetisation was supposed to eradicate it.
He's questioning the time, he's not questioning all that money that's been
seized!
"Mr. Shivakumar's mother hit out at Mr. Siddaramaiah accusing him of not
protecting her son."... ideal mother
Add new comment