‘Karnataka has emerged as the innovation leader in India’

May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Udupi, May 2: During the lockdown period the Department of Public Library digitised more books to the Karnataka Digital Public Library (KDPL).

According to the data released by the KDPL issued here on Saturday , as on April 29, 89,239 people from the State have already registered for the digital library.  From these 1,807 are from Dakshina Kannada district and 605 from the Udupi district.

The digital library already has a repository of 35,500 e-books, 4,800 videos, 59,980 e-journals and 1,112 items for children.

Dubai, Feb 11: An Indian national has been diagnosed with the novel coronavirus in the UAE, bringing the total number of confirmed infection cases to eight, the country's health ministry has said.

The death toll in China's coronavirus outbreak has gone up to 1,016 while the confirmed cases of infection have soared to 42,638, Chinese health officials said on Tuesday.

The UAE Ministry of Health and Prevention (MoHAP) said on Monday that the Indian national was infected after he interacted with a recently diagnosed person.

"The Ministry of Health and Prevention announced today the eighth confirmed case of new coronavirus in the UAE, which is an Indian national who had interacted with a recently diagnosed person," it said in a tweet.

On Sunday, the ministry said that the two new patients, a Chinese national and a Filipino, had been diagnosed with the disease and were receiving medical care as per the highest health standards available in the country.

It said that all health facilities will continue to report any new cases suspected to have coronavirus.

Last week, a family of four who arrived from Wuhan for a holiday in Dubai were diagnosed with coronavirus. A fifth patient, who also arrived from the Chinese city, was confirmed to have been infected with 
the virus, but is reportedly in a stable condition.

China and countries around the world are scrambling to contain the spread of coronavirus which fiirst surfaced in Wuhan city in the Central Hubei province of China. Apart from China, two deaths have occurred in Hong Kong and the Philippines.

Besides Germany, Britain and Italy, other European nations with cases of the virus include France, Russia, Belgium, Sweden, Finland and Spain.