Laughing at yourself may be good for mental well-being

Agencies
February 12, 2018

London, Feb 12: People who frequently crack jokes about themselves to gain approval of others have greater levels of psychological well-being, a study has found.

The findings, published in the journal Personality and Individual Differences, contradict some of the research carried out to date in the psychology of humour.

Up until now, a significant deal of the research literature has suggested that self-defeating humour is exclusively associated with negative psychological effects among individuals who regularly employ this style of humour.

"In particular, we have observed that a greater tendency to employ self-defeating humour is indicative of high scores in psychological well-being dimensions such as happiness and, to a lesser extent, sociability," said Jorge Torres Marin from University of Granada in Spain.

"The results, as well as being consistent with the positive connotations traditionally attributed to the act of 'laughing at oneself' in our country, also suggest that the effects of self-defeating humour on well-being may differ depending on where the research takes places," Marin said.

"Consequently, we believe it is necessary to conduct new studies aimed at analysing potential cultural differences in the use of this kind of humour," he said.

"Our research fits into one of the theoretical models that aim to overcome these limitations and provide the psychology of humour with a well-founded, accurate theoretical body of knowledge," said Hugo Carretero Dios, from University of Granada.

Nonetheless, researchers also point out that certain styles of humour may be employed to conceal negative intentions and feelings.

"Humour enables individuals with low scores in honesty to build trust, closeness, etc. with other people and thereby use important information in order to manipulate them or obtain advantages in the future," said Gines Navarro-Carrillo from University of Granada.

The results regarding the relationship between the use of humour and anger management suggests that the capacity for maintaining a humorous perspective in adverse situations, ie the use of self-enhancing humour, is typically found among people who manage anger more effectively, as well as among those with lower tendencies to exhibit angry feelings or reactions.

By contrast, people who tend to use aggressive or self- defeating humour do not manage anger or rage as well.

In particular, aggressive humour is mainly associated with the expression of anger towards others and a greater propensity to experience anger in everyday life.

By using aggressive humour, individuals may express negative feelings (for example, anger, superiority, hate, etc) less explicitly than they would through physical or verbal abuse, since they can allude to the humorous nature of the comments they make in order to justify them.

Self-defeating humour was linked to a greater tendency to suppress anger. However, this suppression does not necessarily mean that the anger directed at others is reduced or controlled, but rather that the triggers eliciting such angry reactions are concealed or not explicitly stated.

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Agencies
April 17,2020

Washington DC, Apr 17: In recent research, scientists have linked the emotional, social and psychiatric problems in children and adolescents with higher levels of genetic vulnerability for adult depression. The study implies that the genetics passed from parents may be linked with psychiatric problems in children and adolescents and may also leading to depression in adults.

University of Queensland scientists made the finding while analysing the genetic data of more than 42,000 children and adolescents from seven cohorts across Finland, the Netherlands, Norway, Sweden and the UK.

Professor Christel Middeldorp said that researchers have also found a link with a higher genetic vulnerability for insomnia, neuroticism and body mass index.

"By contrast, study participants with higher genetic scores for educational attainment and emotional well-being were found to have reduced childhood problems," Professor Middeldorp said.

"We calculated a person's level of genetic vulnerability by adding up the number of risk genes they had for a specific disorder or trait and then made adjustments based on the level of importance of each gene We found the relationship was mostly similar across ages," Middeldorp added.

The results indicate there are shared genetic factors that affect a range of psychiatric and related traits across a person's lifespan.

Middeldorp said that around 50 per cent of children and adolescents with psychiatric problems, such as attention deficit hyperactivity disorder (ADHD), continue to experience mental disorders as adults, and are at risk of disengaging with their school community among other social and emotional problems.

"Our findings are important as they suggest this continuity between childhood and adult traits is partly explained by genetic risk," the Professor said.

"Individuals at risk of being affected should be the focus of attention and targeted treatment," Middeldorp continued.

"Although the genetic vulnerability is not accurate enough at this stage to make individual predictions about how a person's symptoms will develop over time, it may become so in the future, in combination with other risk factors. And, this may support precision medicine by providing targeted treatments to children at the highest risk of persistent emotional and social problems," Middeldorp added.

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Agencies
June 22,2020

A team of scientists has produced first open source all-atom models of full-length COVID-19 Spike protein that facilitates viral entry into host cells – a discovery that can facilitate a faster vaccine and antiviral drug development.

The group from Seoul National University in South Korea, University of Cambridge in the UK and Lehigh University in the US produced the first open-source all-atom models of a full-length S protein.

The researchers say this is of particular importance because the S protein plays a central role in viral entry into cells, making it a main target for vaccine and antiviral drug development.

"Our models are the first full-length SARS-CoV-2 spike (S) protein models that are available to other scientists," said Wonpil Im, a professor in Lehigh University.

"Our team spent days and nights to build these models very carefully from the known cryo-EM structure portions. Modeling was very challenging because there were many regions where simple modeling failed to provide high-quality models," he wrote in a paper published in The Journal of Physical Chemistry B.

Scientists can use the models to conduct innovative and novel simulation research for the prevention and treatment of Covid-19.

Though the coronavirus uses many different proteins to replicate and invade cells, the Spike protein is the major surface protein that it uses to bind to a receptor.

The total number of global COVID-19 cases was nearing 9 million, while the deaths have increased to over 467,000, according to the Johns Hopkins University.

With 2,279,306 cases and 119,967 deaths, the US continues with the world's highest number of COVID-19 infections and fatalities, according to the CSSE.

Brazil comes in the second place with 1,083,341 infections and 50,591 deaths.

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Agencies
March 27,2020

New Delhi, Mar 27: The Centre has restricted sale and distribution of "hydroxychloroquine" declaring it as an essential drug to treat the COVID-19 patients and meet the requirements of emergency arising due to the pandemic.

The Ministry of Health and Family Welfare on Thursday made the announcement making it clear that the order "shall come into force on the date of its publication in the official Gazette".

In the order, the government declared that the Central government is "satisfied that the drug hydroxychloroquine is essential to meet the requirements of emergency arising due to pandemic COVID-19 and in the public interest, it is necessary and expedient to regulate and restrict the sale and distribution of the drug 'hydroxychloroquine' and preparation based thereon for preventing their misuse".

"Now, therefore, in exercise of the powers conferred by Section 26B of the Drugs and Cosmetics Act, 1940 (23 of 1940), the Central government hereby directs that sale by retail of any preparation containing the drug Hydroxychloroquine shall be in accordance with the conditions for sale of drugs specified in Schedule H1 to the Drugs and Cosmetics Rules, 1945."

The order came at a time when the novel coronavirus claimed 16 lives and infected over 600 people across India.

The announcement regarding ban of sale and distribution of the drug was made by the government earlier but it issued an official Gazette notification on Thursday signalling that hydroxychloroquine -- an anti-Malaria drug -- will work as a medicine for treating coronavirus infected patients as well.

Recently, the national task force for COVID-19 constituted by Indian Council for Medical Research (ICMR) has recommended hydroxy-chloroquine as a preventive medication.

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