Living near gym may make you slimmer

Agencies
January 6, 2018

People who live close to gyms, pools and playing fields weigh less and have smaller waistlines than their counterparts residing farther away from exercise facilities, a UK study suggests.

Living far away from fast food outlets also appeared to help people maintain a lower weight and trimmer waist, although this connection wasn’t as strong as the proximity of gyms, researchers report in the Lancet Public Health.

“It is likely that communities without the neighborhood resources needed to encourage a healthy lifestyle put their residents at a higher risk of obesity,” said senior study author Steven Cummins of the London School of Hygiene & Tropical Medicine.

“This could be improved by restricting the number of new fast food outlets in a neighborhood and how close they can be to people’s homes, incentivizing operators of physical activity facilities to open in residential areas with few facilities, or funding local authorities to provide such facilities,” Cummins said by email.

Globally, more than 1.9 billion adults are overweight or obese, according to the World Health Organization. The condition contributes to a variety of common medical problems including heart disease, diabetes and certain cancers.

For the study, researchers examined data on weight, waist measurements and body fat for more than 400,000 men and women ranging in age from 40 to 70.

The study used data collected between 2006 and 2010 that included demographic characteristics like household income, as well as what types of eating and exercising options were available near people’s home addresses.

To determine exercise opportunities, researchers looked for indoor and outdoor facilities for sports and leisure activities such as gyms, swimming pools and playing fields. They didn’t consider public parks or cycling and walking paths.

On average, people had just one exercise facility within 1 kilometer (0.62 miles) of home. And almost one-third of participants had no options this close to where they lived, the study found.

People typically had to travel just 1.1 kilometers (0.68 miles) to reach a fast food outlet. Nearly one in five people had a fast food restaurant within a half-kilometer (0.31 miles) of home.

Better access to exercise options translated into a healthier weight.

Compared to people who had no facilities near home, people who had at least six places to work out weighed less, had a 1.22 centimeter (0.47 inch) slimmer waistline, and had a body fat percentage that was 0.81 percent lower on average.

At the same time, people who lived at least 2 kilometers (1.24 miles) from a fast food outlet had a waistline 0.26 centimeters (0.10 inches) smaller than individuals who lived less than a half-kilometer away, the study also found.

One limitation of the study is that not all fast food restaurants may have been included in the database, the authors note. The study also didn’t account for the proximity of healthy dining establishments near home, or the type of food and workout options close to where people worked.

The study was not a controlled experiment designed to prove whether or how neighborhood characteristics like the availability of gyms or greasy spoons might impact obesity rates.

It’s hard to rule out the possibility that healthier people may choose to live near the amenities they need to stay healthy, said Pablo Monsivais, author of an accompanying editorial and a nutrition and exercise researcher at Washington State University in Spokane.

But the study still suggests that where we live matters, Monsivais said by email.

“Individually, each of us makes choices that affect whether we maintain a healthy weight or put on pounds, but these choices are shaped by the environments we inhabit,” Monsivais added. “This study looked at just a few features of the environment, but research shows that things like green space, walkability, noise, air quality and the availability of healthy food choices all seem to matter for our health and body weight.”

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Agencies
June 4,2020

The World Health Organisation on Wednesday said that anti-malarial drug hydroxychloroquine (HCQ) will return to the solidarity trial for the potential treatment of coronavirus disease.

At a press conference in the WHO headquarters in Geneva, Director General Tedros Adhanom Ghebreyesus said: "On the basis of the available mortality data, the members of the committee recommended that there are no reasons to modify the trial protocol. The Executive Group received this recommendation and endorsed continuation of all arms of the solidarity trial, including hydroxychloroquine."

The world health body had temporarily suspended the usage of HCQ from the solidarity trial for coronavirus treatment on May 25 soon after a study published in one of the most reliable medical journals, which had suggested that the drug could cause more fatalities among COVID-19 patients.

However, the WHO chief said that the decision was taken as a precaution while the safety data was reviewed.

Ghebreyesus also said that the Data Safety and Monitoring Committee will continue to closely monitor the safety of all therapeutics being tested in the solidarity trial.

"So far, more than 3,500 patients have been recruited in 35 countries. WHO is committed to accelerating the development of effective therapeutics, vaccines and diagnostics as part of our commitment to serving the world with science, solutions and solidarity," he said.

Soon after HCQ was suspended from the trial, the Indian government had said that the antimalarial drug has been known for its benefits for a long time and its usage will be continued on the frontline workers, including police and healthcare professionals, as prophylaxis. The government had also said that studies were being conducted and the drug would be included in the clinical trial also for the treatment of coronavirus disease.

US President Donald Trump also had strongly advocated the use of HCQ and called it a "game-changer". He went to the extent of saying that he had taken the medicine.

Launched by WHO and partners, solidarity trial is an international clinical trial to find an effective treatment for COVID-19, including drugs to slow the progression of the disease or improve survival. The trial, which enrols patients from different countries, "will compare four treatment options against standard of care to assess their relative effectiveness against COVID-19", said WHO. 

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Agencies
June 10,2020

Early treatment with the antiviral drug remdesivir has been found to reduce viral load and prevent lung disease in macaques infected with SARS-CoV-2 that causes COVID-19, according to a study.

The findings, published in the journal Nature on Tuesday, support the early use of remdesivir treatment in patients with COVID-19 to prevent progression to pneumonia.

Researchers from the National Institutes of Health in the US noted that remdesivir has broad antiviral activity and has been shown to be effective against infections with SARS-CoV and MERS-CoV in animal models.

The drug is being tested in human clinical trials for the treatment of COVID-19, they said.

Researcher Emmie de Wit and colleagues investigated the effects of remdesivir treatment in rhesus macaques, a recently established model of SARS-CoV-2 infection.

Two sets of six macaques were inoculated with SARS-CoV-2.

One group was treated with remdesivir 12 hours later -- close to the peak of virus reproduction in the lungs -- and these macaques received treatment every 24 hours until six days after inoculation.

In contrast to the control group, the researchers found that macaques that received remdesivir did not show signs of respiratory disease, and had reduced damage to the lungs.

Viral loads in the lower respiratory tract were also reduced in the treated animals; viral levels were around 100 times lower in the lower-respiratory tract of remdesivir-treated macaques 12 hours after the first dose, they said.

The researchers said that infectious virus could no longer be detected in the treatment group three days after initial infection, but was still detectable in four out of six control animals.

Despite this virus reduction in the lower respiratory tract, no reduction in virus shedding was observed, which indicates that clinical improvement may not equate to a lack of infectiousness, they said.

Dosing of remdesivir in the rhesus macaques is equivalent to that used in humans, the researchers noted.

They cautioned that it is difficult to directly translate the timing of treatment used in corresponding disease stages in humans, because rhesus macaques normally develop only mild disease.

However, researchers said the results indicate that remdesivir treatment of COVID-19 should be initiated as early as possible to achieve the maximum treatment effect.

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Agencies
May 9,2020

17-year-old Pratyusha Jha, wakes up scrambling for newspapers these days to look for any news about her pending board exams and is anxious about what the future has in store for her.

Similar concerns are shared by Bipin Kumar, a class 12 student, who says the announcement of board exams from July 1 to 15 brought limited clarity as the larger questions remain unanswered.

The COVID-19 lockdown, came with a different set of concerns for class 12 students, whose board exams were postponed midway following the outbreak of coronavirus, putting on hold their future plans as well.

"Everyday I have been looking for news about the exams and about entrance exam dates. I feel unfortunate that this happened during the year I was supposed to take the big college leap. I don't want my future decisions to be shaped by this very year as what I opt to study now will remain with me lifelong," Pratyusha told PTI.

Ending some uncertainty for students, HRD Minister Ramesh Pokhriyal 'Nishank' on Friday announced that the pending class 10 and 12 board exams will be held from July 1 to 15. While class 12 exams will be conducted across the country, the class 10 exams are only pending in North East Delhi where they were affected due to the law and order situation.

"The anxiety doesn't end here, there is no date sheet yet. What will be the modalities of exams, how will we reach centres, what protocols have to be followed, there is no clarity on that. My friends and I keep calling our school teachers and also the CBSE helpline to seek some clarity," Bipin Kumar said.

Vaibhav Sharma, a class 12 student in Gurgaon said, "There is no clarity yet. I wanted to apply for DU, but now that the exams are taking place in July when will the results be declared, when will cut offs be announced. If I don't get a good college here, will I be able to travel to different cities for admission, nothing is known yet."

Similarly, for the students in northeast Delhi, the wait for the exams has become a "test of patience" as they were postponed first in the area due to law and order situation, and later due to the coronavirus outbreak, resulting in a four-month-long wait for the exams.

"It has become an endless wait and now I don't feel like studying too. Right from childhood, we are taught that board exams are too crucial and have to be focussed at least two years in advance. But now, it is a different picture altogether," Rani Kumari, a resident of Chandbagh said.

Universities and schools across the country have been closed and exams postponed since March 16 when the Centre announced a countrywide classroom shutdown as one of the measures to contain the COVID-19 outbreak.

Later, a nationwide lockdown was announced on March 24, which has now been extended till May 17.

The board was not able to conduct class 10 and 12 exams on eight examination days due to the coronavirus outbreak. Further, due to the law and order situation in North East Delhi, the board was not able to conduct exams on four examination days, while a very small number of students from and around this district were not able to appear in exams on six days.

The board had last month announced that it will only conduct pending exams in 29 subjects which are crucial for promotion and admission to higher educational institutions. The modalities of assessment for the subjects for which exams are not being conducted will be announced soon by the board.

The schedule has been decided in order to ensure that the board exams are completed before competitive examinations such as engineering entrance JEE-Mains, which is scheduled from July 18-23, and medical entrance exam NEET, which is scheduled on July 26.

The University Grants Commission (UGC) has issued guidelines to universities that new academic session for freshers will begin from September while for the existing students from August.

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