May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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With this 10 crores what are they supposed to do ? It does not work out to them.
WHAT is wrong when our ELECTED LEADERS celebrate the DIAMOND JUBILEE OF VIDHANASOUHDA..KARNATAKA PRIDE.... people /kanadigas must be PROUD of...as any one ask when Political leaders visit and crores are spent...what will be the cost ot HUGE PARTY of 75000 bike riding from all over KARANTAKA..do you think bike owners will participate without benefit.... what kind of TRAFFIC MESS WILL BE THIS... is this not MONEY... We people must consider celebration of any KARNATAKA PRIDE with out leaders...
Whether the Secretariat has heeded to CM's advice? and "..... With this, the plan to gift expensive items to the lawmakers during the celebrations has been dropped." Is it only for the time being and will they get the gifts later on in their office in a "Low Key affair" where nobody will come to know.
Aiyoo swami. Navu irode heege. Foriegn tripu (to study foriegn culture and system and implement in Karnataka), Vidhan Souda habba, seperate religion for lingayats, seperate flag for Karnataka etc etc. All these things must be done by CM and MLA's only. Otherwise the public will get angry that they have voted for non-performers. No other Govt has even thought about this. Great. Really great. Before next election, Siddu, please plan another foriegn trip along with your ministers and MLA's to study the road in developed countries. Ram Linga, neenu England di ge hogi, Scotland Yard police salehe togoli Gouri Lankesh killers na hege hidiyodu anta. Good chance to make a foriegn trip. Nobody will question. Book now. Family noo karkondu hogi. You cannot eat the food there. Your wife can make Jola da rotti with olle mosaru. Bombatu trip. If you have some other plan, then do not take your wife. Alli bread sigute.
Udaya Kumar chennagi helidiri. Innondu maatu. All these at the taxpayers money. Lancha hodiyodu allade kittu kondu tinnodu. Naachike illa ivarige.
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