Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
Hindu brother must think who is GOD and what is truth...most politician are not good hindus they divide people in the name of religion and make innocent people fight each other...who will get benifit..only they..
Naik clearely says that there is no image of GOD, even idol
if hindu brother read veda like we read quran in madras, then they will understand the clear concept of GOD.
no religion book will tell kill another human beign...do you think god himself create human and want to be killer by other...this is stong point..what ever the religion every human is create by GOD and he want us to obey his comendment and live in peace...respect each other
some marons exist in all religion thta does not means all religion people are same.
if we take some example,
hijbul mujeedeen, jaise muhammed ect all kept the name which is related to islam religion and make crime on innocen people
similarly ram sane, bajranga dal, sive sane etc all keept the name which is related to Hindu religion and hide there crime on humanity when they are in trouble.
we human beign must understand that our life is very small say max 90 years,...what we done in this world will be ladder for our sucess after death...we should do good to any human being.
All religious book says same thing
Give maximum benifit to mankind it may be even small work atleast smile...GOD will give mercy on the day of judgement and he loves this kind of person
People should really look what he says , I never found any hate speech from Zakir naik... When we just depend on the lies of this govt. We all are becoming like the donkies who just carry the load of knowledge without knowing that it is carrying loads of knowledge but unable to read... As a Human being We should learn our own scriptures and then make stand if Zakir is telling the TRUTH or LIAR are telling the TRUTH.
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