Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
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Alhamdulillah.. very fortune for mangaloreans, what I see is not many muslims make use of Islamic banks as may be it bacame a habit of using interest banks though they never take interests .. or these banks aren't reaching them .. or any other issue .. recently we planned to buy a flat with a interest loan of 10lakhs , but somewhere we felt like war against Allah ..We dropped it as it involved interest loan .. then suddenly it stroke to my head I can opt for an loan from Islamic bank.. was looking for interest free bank and I found this and same in bangalore as well... In shaa Allah..I hope these bank benefits people like me ..And all Muslims as well..Keeps them away from dealing with interest. May Allah safeguard us from this kind of grave sins
ARE the Cheddi members so WEAK, that they need to be informed that Human life is more valuable than the COW?
Cheddi foot soldiers should use their intellect rather than depending on Cheddi orders and make cow as mother or not.
SEE How Cheddi Foot Soldiers are used by the Cheddis... When they want, they make the CoW the mother. and foot soldiers are used to do violent in the society to protect cow.. and now they even cant control what they sow ...
When PUBLIC Wake up in the society even the cheddis who have 60% will also bow down to PUBLIC... People should note this stand and whenever someone trying to disrupt the society ... The whole like minded society should come together and speak for the truth and give justice...
Spying, cheating, terrorism, looting is their RSS goons birth rights Kurshidji. Nothing can be done and they are digging their own grave.
Simply spoiling their future along with others.. parents all efforts to bring them up went in vain because of the RSS terrorist activities.
bol bachan by yaddi keep. . . lol
Muslims must increase their eemaan to get the help of Allah. Remember 310 Muslims won war against thousands of kafirs. This is the type of help Allah will provide if we become mu'min. Forget this kafirs because Allah has given them the strength inorder to test us. That's it.
This RSS is a real anti human group. Send all those chaddis to andaman nicobar islands
They all belongs to sri rama sene and all from criminal background, put them behind bar for 2 years
Ek baar haji walo ki khidmat ke liye hame bhi mauka diya jaye aur isi bhane allah ke ghar ki ziyarat bhi ho jayegi
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