Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
According to a report published in Jayakirana, a Mangaluru based Kannada eveninger on Thursday, the incident took place on Saturday, but it came to light belatedly. The same report was published in Varthabharati Kannada daily on Friday.
Comments
GO RAKSHAK IS AN IMPOTENT TEAM. If they are really worried for Cow. They should come together to punish BJP men. It clearly shows that they are not worried for cow, they just want to get the benefit from cow voters during the election.
Saffron party not worried for cow. They are utilizing cow for their vote bank. If they are real worried then how India reached no.1 position in beef exporting, and modi government gives discount on the import of beef cutting machinary. Hindu people blindly believe their leaders and they utilize their voters like cow.
Complete F A K E NEWS....
Just saying 'According to the reports'......
Register a case IF the REPORT S are TRUE......
WHY hesitating, Aaj Ka Yudhistir?????
saffrons like eating beef very much than other ....
give them cow dung to eat and cow urine to drink. come on go rakashak
chaddigalu saar chaddigalu
Naren go ka mutra peene ko gaya....
Where are go rakshak sangh who usually force like this people to eat Gomuthra and Cowdung ? Why this time they disappear?
Go(ld) Mutra effect....
Everybody knows who are the real mafia. What can we expect from them when they made india no.1 by selling/exporting their so called gowmatha flesh into the international market .
ha ha ha,,naren thailand where are u?
Real face of BJP in india,.
this s totally fake news.
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