Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
What is ur problem Mr ,go and do ur business don't interfere in our rights.
Someone must check Christina's adhar card sorry, ur id card Whether she Indian or not.
For my sisters you don't go to such college you can go to Madarasha it's best for you in this life and hereafter best education where you get .for the principal first change ur name.
why you send muslim girls to clg.. let them sit at home and help your parents problem is slowed. PFI brother dont waste your time and do not encourage
why muslim girls students using mobile can you stop tiz some of our muslim girl students roaming inside city centre can you stop tiz mybrother
go and wacth inside city centre on friday after many our commuinty student weariing hijab and roaming with their boy friend kindly try to stop tiz
I request the principles sister to were a normal dress insted of religious dress she is wearing , let her be an example for the rules she has set.
I am asking now only muslims wake up when any some so called muslims their marriges arraenging in this christhian churches why? in mangalore no muslim marrige halls ? these all are only for gimik. The college was against the sharia simply, change the college why this college only. if done like this this kind of all colleges they learn lesson .
Their marriage halls we have issue their they cooking haram things & we also cooking hallal then we no problem, because this all our dignity .throw your dignity follow Quran & Sunnah and became original muslim
If clg rules are against democracy we hv to chnge clg rules not our rights.
When injustice becomes law be on the side of justice
thn islam is peace & beautiful bt the systems are against islam thn this islam also hv certain stratagy & thts thought by prophet (s.a)
Secular? If right to cover the head is not secular for you, then there are million christians/hindu women out there wearing head scarfs including former President Prathiba Patil. So, you mean to say that they all cannot have education in India?
Ughhhhh. Individual choice yes. But college has certain rules. You don't want to follow the rules, you don't join that particular college. Also, Islam is a very beautiful religion. Let's not make it all about the Hijab.
100% they are Indians as they are fighting for their rights which is guaranteed by INDIAN CONSTITUTION. Now could you pls chek your voter ID and of the Principal who made rules against the constitution which is legally termed as Anti-Indian rule.
How can this Principal wearing head scarf frame college laws which is against to the constitution of India. Why she is allowing her sibling nuns wearing Hijab like dress and head scarf attend classes in the same college? What is her hidden agenda? How can she justify her draconian dictat??
Someone must check the voter IDs of protesters to find out whether they are really Indians
Why do these bigots go to a secular college if they want Taliban rules?
At one side head of the institutions are wearing head scarf and allowing Christion nuns whose dress code includes head scarf to follow their tradition. On the other side they are objecting Muslim girls to wear head scarf which is similar as their scarf. May I call it as #hypocrisy
Please decent girls don’t go to that college.
Students all are equal in the college
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