Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.
However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.
New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.
The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.
It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.
"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.
As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.
"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.
"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.
To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.
At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.
Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.
In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.
They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.
Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.
The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.
Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.
Comments
Good to see new names occurring to defame Minorities.. Keep going guys.. I guess many new names are on the way still to mock Minorities.. Good luck.. God Bless you..
Some in this thread are proud of being Hindu Nationalist and people like me are proud being Indian Muslim...
And thats why my country name comes first.....
Nevertheless, the so called fake bajrangis. chaddis etc... can't be called patriots of our country. because they dont beleive in unity and they always want to divide country in the name of religion and no matter how much they try.....they will never be successful
As a Hindu, I am proud of Nikhithraj , who had expressed anger against those who raise anti-national slogans and backstab motherland. Whatever my friend Nikhithraj had said that is 100% correct.
A SIMPLE TRUTH
80% of JNU students are Hindus, that is also from Northern India, where Northern India called as Hub of Hinduism.
How these people can be anti national or committed sedition.
The students and staff both are against the central gov't. They are indeed intelligent students, staff in JNU, unlike some others.
You Bhajees label yourself as the only Patriots and others as anti nationals. If you are a true patriot, be obedient to the National constitution. Even you are not a pure Hindu. You are spoiling the name and image of Hindu culture. Because of your ideology Hinduism is very faster diminishing and other religions like Christianity and Islam is growing at the fastest rate which was never before.
Any way, if not you, at least your offspring are coming out from your clutches and following the right path but not your portrayed Hindu culture. They will be real Hindus. If they are real Hindus, then they will choose what they have to be.
Its nice to see so many Hindu brothers and sisters are gathered in colourful function ...what is the main agenda behind this kind of gathering to prove what ? Provoke one community against another ? .. Its true government should take an proper action against goons who had called anti national slogan .. and its clearly shown who were there behind this drama.
As we all seen SDPI or any of its wing never done something wrong which divide india or effect our Indian democracy and it seems they are the who trying to save indian secularism, but we feel RSS and its wings always tried to divide india by religion or cast and they always raise their saffron flag instead of Tricolour Indian Flag.
People should think about political , religious or any party leaders, they are getting their daily bread from where ? Look at the past history of MP, MLA and other members ..they all given hate speech and recognized by people and later they forget them as well.
here we should use our common sense.. regardless of religion for our daily bread and other things we common man should work hard.. there is no logic behind hate one another ... no single common person will get tax free life, no one will wave up our utility bills or supply daily food ... so we all should stand as Indian to show the power of India ..
Hindu Samavesha - only hate and politics speech????
No any good message from the Hindu religion??
IF RSS AND BD HAS REAL LOVE TO OUR MOTHER LAND INDIA THEY NEED TO RAISE THE NATIONAL FLAG NOT THEIR SAFFRON FLAG ..
Y R U RAISING THE SAFFRON COLOR FLAG PLEASE DONT TEACH US THE TO LOVE THE NATION WE KNOW VERY WELL THAN UU
WE MUSLIMS AND CHRISTIANS AND OTHER RELIGIONS WE KNOW.. WE LOVE OUR INDIA MORE THAN UUUU ,
YOU ARE ACTING LIKE THAT U R THE ONE RSS AND BD WHO DIRECTLY FIGHT WITH BRITISH AND MADE INDIA INDEPENDENT..
.
U R ANTI NATIONALS ATTACKING CLUB, LADIE, BAR , COLLEGES SCHOOLS, BEEF EATERS, CHURCHES, MOSQUE ..
DID U HEAR TILL NOW THAT CHRISTIAN AND MUSLIM COMMUNITY ATTACKED THE TEMPLE, BARS, CLUBS? AND BECAUSE OUR RELIGION DOES NOT TEACH US THAT TO ATTACK THE INNOCENT ..
U R THE ONE WHO EDITED THE AUDIO OF JNU TO ANTI SLOGAN NOT US AND IT PROVED......
THIS IS U R ACCHE DIN WHA WHA WHA... U RECIEVED BIHAR RESULT RIGHT WAIT AND SEE IN FUTURE,,
SDPI is a part of BJP, they help gain more seats in recently held election....
oppose modi, oppose BJP, oppose RSS but dont support Pakistanis or who wants to divide India whose slogans are anti national.
anti-national elements who shouted anti-India slogans, should be detained quickly.
Anti-national slogans r not at all good.. But what our govt.is doing? shoot them to kill.
totally wrong statement.
My heart cries after seeing those people who shouted anti national slogans. Shame on you.
who gave rights to univ students to endorse anti India slogans, congress gaining, but still loosing, truth always stand next to BJP
Anti National Slogans are Minor Issues\ - Paid MSMS YET they all are barking endlessly over this issue!! Strange!"
Freedom of speech doesn't mean you raise anti-national slogans.
If anti-national slogans are raised & then they are supported,I think there can be nothing worse than that
I feel angry over anti-national slogans raised in some universities. this people should be in jail for life time.
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