May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
KAR-NATAKA...
:(
Most of the picture shows they are laughing also the police.. Which raises question of understanding!
Der was a statement frm our Dept regarding d stiff action. Is dis called stiff action?
Stiff action wud b a reality if scenario was different, if muslims was protest without permission.
Double standard
why laathi is not working here ??
Enough drama...Dirty politics...
Wah eth maryadeyna janaklu.. and oh my deware what a huge huge dozens of crowds.. oh my deware i cant even count how many they are :D
You foolish guys, Tippu did not destroy temples but in fact he built them and renovated them all....
In fact you destroyed babri masjid a few years back....how bad you guys are....moreover killing innocent muslims at that time and as well during modi's regime in Gujrath...bad people....
Tippu Zindabad!
How they laugh each other like children are playing. this is nothing else they know each other very well because both are chaddis.
In delhi how they drag Najeeb's mother .
well done BJP protest till end.
Kateel is a elected Member of Parliament. He should keep it in mind that all community from his constituency voted for his current position.
Every indian can protest. Then why Mr. Kateel is not participating in Muslim or Christian community protest?? Amazing
discrimination.
Wa/ Wa Master Kateel you Criminal looters thought to do some Loot Pat because of the Great Warriors Name!!!!!! Bap Ray Bap Which Part of the world you are in??? when you Criminal Looters thinking what?? we all understand you are all workless and how long you can leave this type of Life???? what you think being MP??
Never ever see like you Buffoon!!!
\Every Dog has its own day Kateelanna\"
Jai Hoo Siddanna,
Jai Hoo Parmarashwaranna."
let them do jayanthi or kabur whats the problem for u guys. please leave the place and queue up in the bank to exchange the notes.
Most of pics.. laughing each other. Protesters & Police.
conspiracy between Protesters and Police \YOU PRETEND LIKE BEATEN UP AND I PRETEND LIKE BEATING UP\""
Why police released all of this Gundas. Police should have done lati charge and put all of them behind bar under gunda act. Instead of carrying them like babies police could have beaten them with lati. Because of these anti national elements ad terrorists our india is in danger. Please punish them all including our useless MP.
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