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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Aligarh, Jan 14: Uttar Pradesh Minister Raghuraj Singh has courted a major controversy after he said that people who raise slogans against Prime Minster Narendra Modi and Uttar Pradesh Chief Minister Yogi Adityanath "would be buried alive".

The minister said this on Sunday while addressing a rally in Aligarh to muster support for the Citizenship Amendment Act (CAA) 2019.

"If you raise slogans against Prime Minister Narendra Modi or Chief Minister Yogi Adityanath, I will bury you alive," he threatened.

He was apparently referring to protests held by students of Aligarh Muslim University against the CAA during which they allegedly raised slogans against the Prime Minister and the chief minister.

The minister further said: "These one per cent people are opposing the CAA. They stay in India, eat up our taxes and then raise 'murdabad' slogans against the leaders. This country belongs to people of all faiths, but slogan shouting against the Prime Minister or chief minister is unacceptable."

He also launched an attack on India's first Prime Minister Jawaharlal Nehru. "What was Nehru's caste? He did not have a 'khaandan'," he claimed.

Raghuraj Singh is minister of state in the labour ministry in Uttar Pradesh.

New Delhi, Feb 12: Senior Karnataka BJP leader Umesh Katti, who has been left out of the latest cabinet expansion, on Wednesday met party president Jagat Prakash Nadda over the issue.

On Tuesday, Karnataka Chief Minister BS Yediyurappa allotted portfolios to 10 newly inducted ministers. The leader was sulking after he was left out from the cabinet.

According to sources, Katti urged JP Nadda to consider his seniority in the party and give him a ministerial berth.

Earlier, Yeddyurappa had announced that Umesh Katti would be given a place in the state cabinet, but his name was dropped from the list of ministers at the last moment.

According to sources, Umesh Katti also urged Nadda for a Rajya Sabha berth for his brother Ramesh Katti.