May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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drama show of police and sanghis
Check how nicely police behaving with these terrorists.
Well scripted drama by police, admin. & RSS+Congress
why policemen are smiling instead of canning the protesters?
Ramanath Rai should be arrested not bhat, who has saved Kalladka and entire dakshina kannada from anti-national community.
Bhattanige bhattre support....
he should be deported
Drama show of Police, Sanghi and also Kalladka Bhatta and Ramanath Rai. it was a well planned propaganda in view of coming election, look at the body language between police and Sanghis, how friendly.... but same behaviour not seen when Commissioner office Chalo Protest done by Muslims....
waste of energy poor cops
islamic millitants trying their level best to put RSS leaders into jail . But they dont know they will have long standing repercussions in coastal as chutiya congress parties days are numbered .we hindus must see this ISIS muslims act and unite and brutally crush their vote bank politics .slipper must be thrown towards those who follow pseudo secularism and who stand with pakistanis.
India is full of drama, blow their asses, police also are dramabaaz
attack .......lathi charge. arrest and put behind the bars of bellary.
Full DRAMA with no Audience...
Why is police acting , Why cant they use their Laati just like they used for innocent who was demanding justice for quraish.
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