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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jun 28: The Karnataka government on Saturday issued an order, directing private hospitals not to deny treatment to patients with coronavirus and COVID-19 like symptoms.

"Non-compliance of this order will attract punishment under sections of Disaster Management Act 2005," an order read.

Meanwhile, people coming from Maharashtra will be placed in seven-day institutional quarantine followed by seven-day home quarantine in Karnataka, the state government said.

People coming from other states will need to undergo 14-day home quarantine.

Mangaluru, Feb 28: Sleuths of Bajpe police station have busted a counterfeit currency racket and arrested two persons on charge of printing and circulating fake currency notes of Rs 500 and Rs 200.

The arrested have been identified as Dheerendra (45), a resident of Kanjilakody House in Bantwal taluk, and Sudheer Poojary (44), a resident of Adyar Volabail. Both of them said to be activists of Hindutva groups and had campaigned for BJP during last Lok Sabha polls.

Apart from counterfeit currencies, the cops have recovered a colour printer, two mobile phones and a motor bike from the accused.

According police, on February 23 the miscreants went to a petty shop owned by one Abdul Salam near Suralpady and purchased a Gillette blade costing Rs 20. They handed over Rs 200 currency note to Abdul Salam and took Rs 180 back from him.

However, the shop keeper grew suspicious about the genuineness of Rs 200 note. When he went in search of the duo, he came to know that they had purchased mustard seeds from a nearby provision store belonging to one Muhammad Arif. There too, they had handover Rs 200 fake note and got change.

The duo then took fake notes back from Abdul Salam and Muhammad Arif and escaped. The next day, Abdul Salam filed a complaint with Bajpe police station.