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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, May 25: Heavy rain accompanied by strong winds that lashed Bengaluru last evening left hundreds of trees uprooted near the BTM layout and other areas.

The India Meteorological Department (IMD) has predicted a thunderstorm accompanied with lightning in Karnataka for the next five days.

"Thunderstorm accompanied with lightning at will prevail at isolated places over Gangetic West Bengal, Odisha, Coastal Andhra Pradesh and Yanam, South Interior Karnataka, Kerala and Mahe and Tamilnadu, Puducherry and Karaikal," the IMD said its All Indian Weather Forecast Bulletin.

According to the forecasting agency, due to strong southerly wind from the Bay of Bengal to northeast India at lower tropospheric levels, heavy to very heavy rainfall with extremely heavy falls likely at isolated places over parts of northeastern states.

In addition to that heavy to very heavy rainfall at isolated places over adjoining parts of east India during 24th-28th. "Heavy rainfall at isolated places over parts south peninsular India from May 26th-28th, 2020," the IMD said its All Indian Weather Forecast Bulletin.

Bengaluru, Mar 14: Amid coronavirus threat, Karnataka Chief Minister BS Yediyurappa has ordered shutting down for a week of all places/activities where people gather in large number including swimming pools, shopping malls, schools, colleges, cinema halls etc, state Health Minister B Sriramulu said.

This comes after Yediyurappa chaired an emergency meeting with ministers and senior officials on Friday to discuss the situation.

Earlier, schools in the state had announced early summer vacation for their students this academic year as a precautionary measure. Other public places have been shut down in the state amid the Covid-19 scare.

The shut down in Karnataka comes after various other state governments ordered similar steps. Uttar Pradesh, Kerala, Jammu and Kashmir etc. are some of the states where governments have ordered shut down as a precautionary measure to contain the spread of the deadly coronavirus.

The central government has also taken several steps to contain the virus, including suspension of all visas to India till April 15. Till date, India has reported two deaths and 82 confirmed cases of the deadly coronavirus.

The World Health Organisation (WHO) has declared the coronavirus outbreak a pandemic. The virus, which originated in the Chinese city of Wuhan last year has spread to more than 100 countries worldwide, infecting over 1,30,000 people.