Kabul, Nov 21: A suicide bomber blew himself up in the Afghan capital Kabul on Tuesday, killing more than 50 people, three government officials said.
Najib Danish, a spokesman for the interior ministry, said more than 70 other people were injured in the attack.
“A suicide bomber detonated his explosives inside a wedding hall where Islamic religious scholars had gathered to commemorate the birthday of Prophet Mohammad,” Danish said.
There were no immediate claims of responsibility for the blast.
Islamabad, Jun 3: Pakistan has reported a record 4,132 fresh cases of the coronavirus in the last 24 hours, taking the total number of infections to 80,463, the health ministry said on Wednesday.
The Ministry of National Health and Services said the new infections were detected after conducting a maximum of 17,370 tests in a day.
Of the total cases, Sindh has so far detected 31,086 patients of the coronavirus, Punjab 29,489, Khyber-Pakhtunkhwa 10,897, Balochistan 4,747, Islamabad 3,188, Gilgit-Baltistan 779 and Pakistan-occupied Kashmir reported 289 patients of the viral disease.
"In total 67 patients died in the last 24 hours, taking the tally of deaths to 1,688. Another 28,923 people have fully recovered from the disease," the ministry said in a statement.
The authorities have so far carried out 595,344 tests in the country.
Officials said that Pakistan has more than 100 labs that can conduct over 30,000 tests per day and the number of daily tests will be gradually increased to the maximum level.
Canadian researchers are developing a DNA vaccine for SARS-CoV-2, the coronavirus that causes COVID-19 and has currently infected nearly 5,00,000 people worldwide and crippled the global economy.
Entos Pharmaceuticals, a health-care biotechnology company headed by a University of Alberta researchers, develop new therapeutic compounds using the company's proprietary drug-delivery platform and has begun manufacturing vaccine candidates against the novel coronavirus.
"Given the urgency of the situation, we can have a lead candidate vaccine within two months. Once we have that it's a race to get it into clinical trials," said John Lewis, CEO of Entos and a Professor at the University of Alberta in Canada.
Lewis said in comparison to a traditional vaccine, DNA-based vaccines hold several advantages.
Nucleic acids are introduced directly into the patient's own cells, causing them to make pieces of the virus--tricking the immune system into mounting a response without the full virus actually being present, the researcher said.
According to the company, the approach is recognised as being easier to move into large-scale manufacturing, offers improved vaccine stability and works without needing an infectious agent.
In the current absence of a vaccine for COVID-19, several companies around the world are mounting efforts to begin similar work.
The first clinical trial using a DNA-based vaccine developed by Moderna Inc.in the US on March 13.
Their approach allows for antibodies to be made in the human trial volunteers against a specific protein on the surface of the coronavirus that lets the virus enter human cells.
The hope is that the antibodies will stop the interaction.
Though this approach is designed to be effective against COVID-19 specifically, Lewis said Entos is taking a different tack.
The company plans to use plasmid DNA to amplify the production of key coronavirus surface and structural proteins with each injection, with an eye to the bigger picture.
"Many of the structural proteins in the virus are pretty well conserved across all the coronaviruses, including SARS and MERS," said Lewis.
"We're hoping that if we express more of the structural proteins that are common to most coronaviruses, we can inhibit the current COVID-19, and also potentially protect against all coronaviruses both past and future," Lewis added.
To move the project forward quickly, the company is seeking financial support from both provincial and federal levels of government.
"We have the opportunity to save a lot of lives, and I think it's really upon us and governments to find solutions for that," Lewis said.
Jan 23: Pakistan's Prime Minister Imran Khan called on Wednesday for the United Nations to help mediate between nuclear armed India and Pakistan over the disputed territory of Kashmir.
"This is a potential flashpoint," Khan said during a media briefing at the annual meeting of the World Economic Forum in Davos, Switzerland, adding that it was time for the "international institutions ... specifically set up to stop this" to "come into action".
The Indian government in August revoked the constitutional autonomy of Indian-administered Kashmir, splitting the Muslim-majority region into two federal territories in a bid to integrate it fully with the rest of the country.
Kashmir is claimed in full by both India and Pakistan. The two countries have gone to war twice over it, and both rule parts of it. India's portion has been plagued by separatist violence since the late 1980s.
Khan said his biggest fear was how New Delhi would respond to ongoing protests in India over a citizenship law that many feel targets Muslims.
"We're not close to a conflict right now ... What if the protests get worse in India, and to distract attention from that, what if ..."
The prime minister said he had discussed the prospect of war between his country and India in a Tuesday meeting with US President Donald Trump. Trump later said he had offered to help mediate between the two countries.
Khan said Pakistan and the United States were closer in their approach to the Taliban armed rebellion in Afghanistan than they had been for many years. He said he had never seen a military solution to that conflict.
"Finally the position of the US is there should be negotiations and a peace plan."
In a separate on-stage conversation later on Wednesday, Khan said he had told Trump in their meeting that a war with Iran would be "a disaster for the world". Trump had not responded, Khan said.
Khan made some of his most straightforward comments when asked why Pakistan has been muted in defence of Uighurs in China.
China has been widely condemned for setting up complexes in remote Xinjiang province that Beijing describes as "vocational training centres" to stamp out ""extremism and give people new skills.
The United Nations says at least one million ethnic Uighurs and other Muslims have been detained.
When pressed on China's policies, Khan said Pakistan's relations with Beijing were too important for him to speak out publicly.
"China has helped us when we were at rock bottom. We are really grateful to the Chinese government, so we have decided that any issues we have had with China we will handle privately."
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